Care at NUH

Adult Liver Transplant

2024/07/17
Adult Liver Transplantation Programme

Adult Liver Transplantation

NUH liver transplantation programme was established in 1990, catering to both adults and children. The services available include pre-transplant medical assessments, surgical and micro-surgical services, post-transplant intensive care and recovery, outpatient check-ups, and lifetime medical reviews.

National University Centre for Organ Transplantation (NUCOT) is a leading transplant centre that performs on average 70% of the liver transplants in Singapore annually, with outcomes comparable to international benchmarks. Our care team ensures that every transplant patient receives one-stop comprehensive, dedicated and individualised care.

We are well-equipped with interventional radiology and endoscopy services – thereby improving graft and patient survival. This is the key to the success of liver transplantation and in managing possible ensuing complications.

Our transplant coordinators and other allied health professionals (such as medical social workers, transplant pharmacists, and dietitians) work together to provide the required support and education to our patients and their caregivers.

Find out more about liver failure and its treatments, frequently asked questions about liver transplant and donating your liver here.

Adult Kidney Transplantation

Liver Transplant Care Team

Directors

Dr Mark Dhinesh Muthiah

Dr Mark Muthiah
Medical Director and Senior Consultant

Associate Professor Iyer Shridhar Ganpathi

Associate Professor Shridhar Iyer
Surgical Director and Senior Consultant

 


Clinicians

Professor Lim Seng Gee

Professor Lim Seng Gee
Senior Consultant

Dr Lee Guan Huei

Dr Lee Guan Huei
Senior Consultant

Dr Lee Yin Mei

Dr Lee Yin Mei
Senior Consultant

Low How Cheng

Dr Low How Cheng
Senior Consultant

Dr Prem H Thurairajah

Dr Prem H Thurairajah
Senior Consultant

Dr Gao Yujia

Dr Gao Yujia
Consultant

Dr Daniel Huang

Dr Daniel Huang
Consultant

Dr Mark Dhinesh Muthiah

Dr Mark Dhinesh Muthiah
Senior Consultant

Dr Pang Ning Qi

Dr Pang Ning Qi
Consultant

Dr Eunice Tan

Dr Eunice Tan
Consultant

Transplant Coordinators

Priscilla Wee

Priscilla Wee
Principal Transplant Coordinator

 

Diana Teh

Diana Teh
Senior Transplant Coordinator

Aye Su Mon

Aye Su Mon
Transplant Coordinator

Brenda Kok

Brenda Kok
Transplant Coordinator

Chloe Tan

Chloe Tan
Transplant Coordinator

Our Experience

To date, NUCOT has performed more than 400 successful adult and paediatric living and deceased donor liver transplantations. We continue to provide post-transplant care and medical follow-ups at our Specialist Outpatient Clinic. On average, we perform about 70% of the total number of liver transplants (both living and deceased donor liver transplants) in Singapore annually.

In 2020, NUCOT performed 75% of the total liver transplants in Singapore (both living and deceased donor liver transplants).1

NUCOT is also a national referral centre for Singapore's deceased liver donations and transplants. In 2020, we performed 63.6% of the total number of deceased donor liver transplants in Singapore.1

Based on 2020 annual report from the Ministry of Health, National Organ Transplant Unit.

Post-Transplant Outcomes

NUH started our first liver transplant in 1990, and since then, our post-transplant outcomes have been recognised internationally. Our clinical outcomes are better than or comparable with international benchmarks. Our post-transplant patient survival and graft survival rates are illustrated in the tables below:

Patient Survival (Living Donor, 2007 – 2020)
 1-year3-years5-years10-years
NUCOT (n=99)90.5%86.0%84.0%78.0%
US188.0%81.0%76.0%67.9%
Europe280.0%75.0%69.0%61.0%
Korea384.1%80.6%*

1 OPTN/SRTR 2015 Annual Data Report: Liver / Transplantation: July 2018 - Volume 102 - Issue - p S24
2 Living donor liver transplantation in Europe HepatoBiliary Surg Nutr 2016; 5(2): 159-175
3 Effect of Institutional Case Volume: Analysis of 7073 Cases Between 2007 and 2016 in Korea. Transplantation. 2019 May; 103(5): 952-958

Patient Survival (Deceased Donor, 2007 – 2020)
 1-year3-years5-years10-years
NUCOT (n=132)93.0%89.0%82.0%75.0%
US187.3%79.4%73.6%59.8%
Europe285.0%79.0%72.0%59.0%
UK391.0%87.0%80.0%66.0%

1 World J Transplant 2018 September 10; 8(5): 167-177
2 ELTR - Transplant International 2018; 31: 1293-1317
3 NHS Blood and Transplant Activity Report 2015/2016. *for 2002-2004 Transplants

Our Medical Achievements

Since 1990, NUCOT has performed more than 400 liver transplants and demonstrated clinical outcomes comparable to international standards. NUCOT has also established many major liver transplant milestones over the years:

  • 1990 - Deceased donor liver transplant for adult patient in Singapore
  • 1996 - Living donor liver transplant for adult patient in Singapore
  • 1997 - Deceased donor split liver transplant in Singapore
  • 2002 - Right lobe graft from a living donor for adult patient in Singapore
  • 2006 - Laparoscopic retrieval on adult donor who donated to paediatric liver patient in Singapore
  • 2010 - Combined liver and kidney transplant on a 16-year-old patient in Singapore
  • 2016 - Altruistic non-directed donor liver transplant in Singapore
  • 2018 - Laparoscopic retrieval on adult donor who donated to adult liver patient in Singapore
  • 2022 - Living donor liver transplant for adult patient with Stage 4 colorectal cancer in the region
NUCOT In The News

2023

2022

Click here for more news related to NUCOT’s kidney transplant.

Contact Us
NUCOT
NUCOT

National University Centre for Organ Transplantation (NUCOT) provides pre and post-transplant patients with comprehensive, dedicated and individualised care. We also welcome potential living organ donors to get in touch with us.

Referrals to NUCOT

NUCOT takes in self-referrals and referrals from healthcare practitioners. Patients can do a self-referral by contacting our NUCOT clinic directly or have your primary physician refer you to us.

Click here for our NUCOT clinic's location, contact details and operating hours or to make an appointment with us.

Resources

Download our PDF brochures:

Information accurate as of June 2024

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