Care at NUH

Paediatric Liver Transplant

2024/07/16
Paediatric Liver Transplantation Programme

Paediatric Liver Transplantation

Our paediatric liver transplant programme at National University Centre for Organ Transplantation (NUCOT) involves the evaluation and management of children with end-stage liver disease prior to transplantation, as well as their post-operative care following transplantation. NUCOT is the National Referral Centre for children up to the age of 18 years in need of a liver transplant for end-stage or metabolic liver disease. We are Singapore's leading and only transplant centre that performs paedatric liver transplants, with outcomes comparable to international benchmarks.

We also recognise the importance of good transition of our paediatric patients to adult care. We run the Adolescent and Young Adult Liver Transplant Transition Clinic where our paediatric liver transplant recipients go through several clinic sessions to prepare themselves and their parents for a smooth transition to adult care.

Find out more about liver failure and its treatments, frequently asked questions about liver transplant and donating your liver here.

Liver Transplant Care Team

Children are cared for by a multidisciplinary paediatric liver transplant team consisting of:

  • Paediatric Liver Transplant Surgeons and Paediatric Hepatobiliary Surgeons
  • Adult Hepatobiliary Surgeons for the Donors
  • Paediatric Transplant Hepatologists
  • Paediatric Transplant Anaesthesiologists
  • Paediatric Intensivists
  • Paediatric Interventional Radiologists
  • Paediatric Infectious Disease Specialists
  • Psychologists
  • Transplant Coordinators
  • Transplant Pharmacists
  • Dietitians
  • Specialist Nurses
  • Medical Social Workers

Directors

Prof Yap Hui Kim

Professor Yap Hui Kim
Medical Director and Emeritus Consultant

Dr Vidyadhar Mali

Dr Vidyadhar Mali
Surgical Director and Senior Consultant

Clinicians

Professor Quak Seng Hock

Professor Quak Seng Hock
Emeritus Consultant

Dr S Venkatesh Karthik

Dr S Venkatesh Karthik
Senior Consultant

Dr Dale Lincoln Loh

Dr Dale Lincoln Loh
Senior Consultant

Dr Vidyadhar Mali

Dr Vidyadhar Mali
Senior Consultant 

Dr Nyo Yoke Lin

Dr Nyo Yoke Lin
Senior Consultant

Dr Michelle Tan

Dr Michelle Tan
Senior Consultant

Dr James Huang

Dr James Huang
Consultant

 

Dr Lee Yang Yang

Dr Lee Yang Yang
Consultant

Specialty Nurses

  • Nurse Clinician Junaidah Binte Abu Bakar
  • Nurse Clinician Pamela Tan

Transplant Coordinators

Priscilla Wee

Priscilla Wee
Principal Transplant Coordinator

Aye Su Mon

Aye Su Mon
Transplant Coordinator

Brenda Kok

Brenda Kok
Transplant Coordinator

Chloe Tan

Chloe Tan
Transplant Coordinator

Diana Teh

Diana Teh
Transplant Coordinator

Our Experience

To date, NUCOT has performed more than 400 successful adult and paediatric living and deceased donor liver transplantations. We continue to provide post-transplant care and medical follow-ups at our Specialist Outpatient Clinic. We perform most of the paediatric transplants, and on average about 70% of the total number of liver transplants (both living and deceased donor liver transplants) in Singapore annually.

In 2020, NUCOT performed 75% of the total liver transplants in Singapore (both living and deceased donor liver transplants).1

Paediatric Liver Transplantation

NUCOT is also a national referral centre for Singapore's deceased liver donations and transplants. In 2020, we performed 63.6% of the total number of deceased donor liver transplants in Singapore.1

Paediatric Liver Transplantation

1 Based on 2020 annual report from the Ministry of Health, National Organ Transplant Unit.

Post-Transplant Outcomes

The first paediatric liver transplant in Singapore was performed in the National University Hospital in 1991. Since then, our post-transplant outcomes have been comparable to international benchmarks.

Overall Graft Survival (1991 – 2021)
 1-year3-years5-years10-years
NUCOT (n=144)86.4%85.7%82.1%85.7%
US190.3%85.4%81.9%78.4%
Europe275.0% 71.0% 68.0%63.0%

 

Overall Patient Survival (1991 – 2021)
 1-year3-years5-years10-years
NUCOT (n=142)89.3%85.7%85.0%84.2%
US194.9%91.4%88.2%70.0%
Europe285.3% 82.5% 80.3%75.8%
1 OPTN/SRTR 2017 Annual Data Report: Liver

2 European Liver Transplant Registry

Our Medical Achievements

​Since 1991, NUCOT has established several major paediatric liver transplant milestones over the years:

  • 1991 - Deceased donor liver transplant for paediatric patient in Singapore
  • 1995 - Reduced liver graft from a deceased donor for paediatric patient in Singapore
  • 1996 - Living donor liver transplant for paediatric patient in Singapore
  • 1997 - Deceased donor split liver transplant in Singapore
  • 2010 - Combined liver and kidney transplant on a 16-year-old patient in Singapore
  • 2014 - Hyper-reduced liver graft from a living donor for the youngest paediatric patient in Singapore
Liver Transplant Support Group

The group provides moral support, encouragement and medical advice for patients stricken with liver diseases as well as their family members. It also promotes greater public understanding and awareness of organ donation.

For more information or to join this support group, please contact us here.

Contact Us
NUCOT
NUCOT

National University Centre for Organ Transplantation (NUCOT) provides pre and post-transplant patients with comprehensive, dedicated and individualised care. We also welcome potential living organ donors to get in touch with us.

Referrals to NUCOT

NUCOT takes in self-referrals and referrals from healthcare practitioners. Patients can do a self-referral by contacting our NUCOT clinic directly or have your primary physician refer you to us.

Click here for our NUCOT clinic's location, contact details and operating hours or to make an appointment with us.

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