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Dr Zhang Yaochun

Designations:
  • ​Senior Research Fellow, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore (Research Specialty: Renal Immunology & Genetics)
Qualifications:
PhD., National University of Singapore (Singapore), M.Sc (Pharm.), Peking Union Medical College (China), B.Sc (Pharm.), Shandong University (China)

Journals & Publications

  1. Yeo WS, Zhang YC (2017). Bioengineering in renal transplantation: technological advances and novel options. Pediatric Nephrology (Berlin, Germany). doi: 10.1007/s00467-017-3706-4
  2. Zhang YC, Yeo WS, Ng KH, Yap HK (2015). CRISPR/Cas9 for genome engineering: the next genomic revolution. Journal of Biochemistry and Molecular Biology Research, 1(4):112-7.
  3. Sun ZJ, Ng KH, Liao P, Zhang Y, Ng JL, Liu ID, … Yap HK (2015). Genetic interactions between TRPC6 and NPHS1 variants affect post-transplant risk of recurrent focal segmental glomerulosclerosis. American Journal of Transplantation : Official Journal of the American Society of Transplantation and and the American Society of Transplant Surgeons, 15(12):3229-38. doi: 10.1111/ajt.13378
  4. Zhang YC, He CN, Chew EH (2013). Studies on the chemical constituents and biological activities of Ixeris. Chemistry & Biodiversity, 10(8):1373-91. doi: 10.1002/cbdv.201100234
  5. Zhang YC, Gan FF, Shelar SB, Ng KY, Chew EH (2013). Antioxidant and Nrf2 inducing activities of luteolin, a flavonoid constituent in Ixeris sonchifolia Hance, provide neuroprotective effects against ischemia-induced cellular injury. Food and Chemical Toxicology : An International Journal published for the British Industrial Biological Research Association, 59:272-80. doi: 10.1016/j.fct.2013.05.058
  6. Ling H, Zhang Y, Ng KY, Chew EH (2011). Pachymic acid impairs breast cancer cell invasion by suppressing nuclear factor-kappaB-dependent matrix metalloproteinase-9 expression. Breast Cancer Research and Treatment, 126(3):609-20. doi: 10.1007/s10549-010-0929-5
  7. He CN, Peng Y, Zhang YC, Xu LJ, Gu J, Xiao PG (2010). Phytochemical and biological studies of Paeoniaceae. Chemistry & Biodiversity, 7(4):805-38. doi: 10.1002/cbdv.200800341
  8. Chew EH, Nagle AA, Zhang Y, Scarmagnani S, Palaniappan P, Bradshaw TD, … Westwell AD (2010). Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention. Free Radical Biology & Medicine, 48(1):98-111. doi: 10.1016/j.freeradbiomed.2009.10.028
  9. Ling H, Jia X, Zhang Y, Gapter LA, Lim YS, Agarwal R, Ng KY (2010). Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells. Molecular Carcinogenesis, 49(3):271-82. doi: 10.1002/mc.20597
  10. Zhang YC, Zhou L, Ng KY (2009). Sesquiterpene lactones from Ixeris sonchifolia Hance and their cytotoxicities on A549 human non-small cell lung cancer cells. Journal of Asian Natural Products Research, 11(4): 294-8. doi: 10.1080/10286020902727520
  11. Zhou L, Zhang Y, Gapter LA, Ling H, Agarwal R, Ng KY (2008). Cytotoxic and anti-oxidant activities of Lanostane-type triterpenes isolated from Poria cocos. Chemical & Pharmaceutical Bulletin, 56(10): 1459-62.


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