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Dr Shawn Lee

Photo of Dr Shawn Lee
  • Associate Consultant, Division of Paediatric Haematology and Oncology, Department of Paediatrics, Khoo Teck Puat - National University Children's Medical Institute, National University Hospital
  • ​Senior Lecturer, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore
MBBS (S'pore), MMed (Paeds) (S'pore), MRCPCH (UK), MCI (S'pore)
Paediatric Haematology & Oncology
Special Interests:
​Immunogenomics and immunotherapyPersonalised therapy and pharmacogenomicsChildhood leukaemia, childhood lymphomaToxicities of oncology treatment such as neutropenic fever


Dr Shawn Lee graduated with MBBS from Yong Loo Lin School of Medicine, NUS in 2011 where he was awarded the Wong Poi Kwong Medal for Clinical Medicine. He went on to obtain his Master of Medicine (Paeds) and MRCPCH (UK) in 2015 and begun subspecialty training in paediatric haematology-oncology. In 2017, he was awarded the Exxon-Mobil Fellowship for Clinicians. During his senior residency in 2017, he served a leadership role of Assistant Chief Registrar. He completed his senior residency and obtained specialist accreditation in Paediatric Medicine in 2019. 

Dr Lee has been awarded the NMRC Research Training Fellowship in 2019, where he will embark on a 2-year fellowship in pharmacogenomics and immunogenomics under Dr Yang Jun in St. Jude Children's Research Hospital in Memphis, USA. His specialty clinical interests are in the areas of childhood leukaemia and lymphoma as well as the toxicities associated with treatment such as neutropenic fever. His research interests include immunotherapy and immunogenomics to aid in prognostication, risk stratification and optimal utilisation of immunotherapeutic agents. He is also invested in individualised therapy in oncology, specifically pharmacogenomics to evaluate drug resistance mechanisms in leukaemia and allow for personalised tailoring of treatment therapy.


Academic Honours and Achievements

  • NUHkids Junior Research Award (Highest Grants) 2018
  • Merit Award, NUHS Clinician Scientist Unit Pitch For Funds Rounds, 2018
  • ExxonMobil-NUS Research Fellowship For Clinicians, 2018
  • Best Oral Presentation, NUHS Clinician Scientist Program Residency, 2018
  • Best Oral Presentation, NUHS Clinician Scientist Program Residency, 2017
  • Best Oral Presentation, NUHS Clinician Scientist Program Residency, 2016
  • Wong Poi Kwong Medal (Best Student in Clinical Medicine), NUS, 2011


  • National Medical Research Council (NMRC) Research Training Fellowship, Nov 2018
  • ExxonMobil-NUS Research Fellowship for Clinicians, July 2018
  • MOH Healthcare Research Scholarship: Master of Clinical Investigation, July 2017


As Principle Investigator

  • 2019-2022: T-cell Receptor Profiling in Children with Acute Lymphoblastic Leukemia
    • Funding Agency: NMRC
  • 2017-2019: T-cell Receptor Repertoire in Children with Acute Lymphoblastic Leukemia
    • Funding Agency: Exxon-Mobil Fellowship for Clinicians
  • 2018-2019: T-cell Receptor Repertoire Recovery after T-cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation
    • Funding Agency: NUHS Clinician Scientist Unit PFFR
  • 2016-2018: Kinetics of Immune and T Cells in Children With Cancer for Immunotherapy (KITCAN)
    • Funding Agency: NUHS Clinician Scientist Program
  • 2016-2017: Oncogene Expression in Asian Children and Adolescents with Osteosarcoma
    • Funding Agency: KTP-UCMI Seed Grant

Journals & Publications

  1. ​Epidemiology of Childhood Malignant Mediastinal Masses and Clinical Factors Associated With Intensive Care Unit Admission: A Singapore Experience. Shawn Lee, Bernice Oh, Miriam Kimpo, TC Quah, Journal of Pediatrics and Child Health, 2019 (in publication)
  2. The Role of NK Cells as A Platform for Immunotherapy in Pediatric Cancers. Miriam Kimpo, Bernice Oh, Shawn Lee, Current Oncology Reports, Curr Oncol Rep. 2019; 21(10): 93.
  3. Pharmacogenomics in Acute Lymphoblastic Leukemia. Shawn Lee, Jun J Yang, Best Practice & Research Clinical Hematology, July 2017, DOI: 
  4. Acronyms in Ophthalmology. Shawn Lee, Woo Jyh Haur, Au-Eong KG, Ophthalmology, Volume 119, Issue 9 , Pages 1939. 1940.e1, September 2012

Professional Memberships

  • ​Member, Paediatric Oncology Group Singapore (Executive committee, 2017)
  • Member, International Society of Paediatric Oncology (SIOP)
  • International Associate Member, American Society of Hematology
  • Member, Royal College of Paediatrics and Child Health


Appt Tel:
+65 6779 7486