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Prof Lee Yung Seng

Designations:
  • Head & Senior Consultant, Department of Paediatrics, Khoo Teck Puat – National University Children's Medical Institute, National University Hospital
  • Senior Consultant, Division of Paediatric Endocrinology, Department of Paediatrics, Khoo Teck Puat – National University Children's Medical Institute, National University Hospital
  • Head & Professor, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore
Qualifications:
MBBS (S'pore), MMed (Paeds) (S'pore), MRCP (UK), FRCPCH (UK), FAMS (Paeds) S'pore), PhD
Specialties:
Paediatrics
Sub-Specialties:
Paediatric Endocrinology (Hormonal & Growth Problems)

Biosketch

Professor Lee Yung Seng is head of the Khoo Teck Puat - National University Children's Medical Institute (KTP-NUCMI), with clinical interests in endocrinology and diabetes. Within KTP-NUCMI, he is head of the Department of Paediatrics and looks after children with problems in growth, puberty and hormonal abnormalities such as diabetes.
 
Prof Lee is also the head of the department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore. He received his clinical training at NUH and specialist training in clinical paediatric endocrinology at the Cambridge University Department of Paediatrics at Addenbrooke's Hospital as well as research training at the University of Cambridge.
 
Prof Lee is awarded the Dean’s Chair, Yong Loo Lin School of Medicine NUS, in recognition of outstanding and impactful scholarly accomplishments.  He is the president of the Asia Pacific Paediatric Endocrine Society (APPES), and the president of the College of Paediatrics and Child Health, Academy of Medicine, Singapore.  Professor Lee has more than 220 peer reviewed publications in the area of childhood obesity, developmental origins of heath and disease, and paediatric endocrinology.


Awards

  • ​Dean’s Chair, Yong Loo Lin School of Medicine, National University of Singapore (1 Nov 2018 to 31 Oct 2021)

Journals & Publications

  1. Ooi DSQ, Ong SG, Lee OMH, Chan YH, Lim YY, Ho CWL, Tay V, Vijaya K, Loke KY, Sng AA, Lee YS. 2022 Feb 7. Prevalence and predictors of metabolically healthy obesity in severely obese Asian children. Pediatr Res. doi: 10.1038/s41390-022-01941-z. Online ahead of print. PMID: 35132129
  2. Ong YY, Pang WW, Huang JY, Aris IM, Sadananthan SA, Tint MT, Yuan WL, Chen LW, Chan YH, Karnani N, Velan SS, Fortier MV, Choo J, Ling LH, Shek L, Tan KH, Gluckman PD, Yap F, Chong YS, Godfrey KM, Chong MF, Chan SY, Eriksson JG, Wlodek ME, Lee YS*, Michael N* (joint corresponding authors). 2022 Feb 6. Breastfeeding may benefit cardiometabolic health of children exposed to increased gestational glycemia in utero. Eur J Nutr. doi: 10.1007/s00394-022-02800-7. Online ahead of print. PMID: 35124728
  3. Ooi DSQ, Ling JQR, Ong FY, Tai ES, Henry CJ, Leow MKS, Khoo EYH, Tan CS, Chong MFF, Khoo CM, Lee YS. 2021 Nov 26;13(12):4245. Branched Chain Amino Acid Supplementation to a Hypocaloric Diet Does Not Affect Resting Metabolic Rate but Increases Postprandial Fat Oxidation Response in Overweight and Obese Adults after Weight Loss Intervention. Nutrients. doi: 10.3390/nu13124245. PMID: 34959797
  4. Ng NBH, Low YW, Rajgor DD, Low JM, Lim YY, Loke KY, Lee YS. 2021 Aug 26. The effects of glucagon-like peptide (GLP)-1 receptor agonists on weight and glycaemic control in Prader-Willi syndrome: A systematic review. Clin Endocrinol (Oxf).
  5. Ooi DSQ, Dorajoo R, Gurung RL, Dehghan R, Lim YY, Ho CWL, Tay V, Karuppiah V, Loke KY, Lim SC, Liu JJ, Sng AA, Lee YS. 2021 Jan 26:e12771. Association of leukocyte telomere length with obesity-related traits in Asian children with early-onset obesity. Pediatr Obes. doi: 10.1111/ijpo.12771. Online ahead of print. PMID: 33501739
  6. Ong YY, Sadananthan SA, Aris IM, Tint MT, Yuan WL, Huang JY, Chan YH, Ng S, Loy SL, Velan SS, Fortier MV, Godfrey KM, Shek L, Tan KH, Gluckman PD, Yap F, Choo JTL, Ling LH, Tan K, Chen L, Karnani N, Chong YS, Eriksson JG, Wlodek ME, Chan SY, Lee YS*, Michael N* (*joint last authors). 2020 Oct 1;49(5):1591-1603. Mismatch between poor fetal growth and rapid postnatal weight gain in the first 2 years of life is associated with higher blood pressure and insulin resistance without increased adiposity in childhood: the GUSTO cohort study. Int J Epidemiol. doi: 10.1093/ije/dyaa143. PMID: 32851407
  7. Chen LW*, Xu J*, Soh SE, Aris IM, Tint MT, Gluckman PD, Tan KH, Shek LP, Chong YS, Yap F, Godfrey KM, Gilbert JA, Karnani N**, Lee YS** (** joint corresponding authors). 2020 Jul;44(7):1508-1520. Implication of gut microbiota in the association between infant antibiotic exposure and childhood obesity and adiposity accumulation. Int J Obes (Lond). doi: 10.1038/s41366-020-0572-0. Epub 2020 Apr 22. PMID: 32321980.
  8. Bernard JY, Pan H, Aris IM, Moreno-Betancur M, Soh SE, Yap F, Tan KH, Shek LP, Chong YS, Gluckman PD, Calder PC, Godfrey KM, Chong MF, Kramer MS, Karnani N, Lee YS. 2018;108(1):92-100. Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants. Am J Clin Nutr.
  9. Tint MT, Chong MF, Aris IM, Godfrey KM, Quah PL, Kapur J, Saw SM, Gluckman PD, Rajadurai VS, Yap F, Kramer MS, Chong YS, Henry CJ, Fortier MV, Lee YS. 2018; 42(7):1296-1305. Association between maternal mid-gestation vitamin D status and neonatal abdominal adiposity. Int J Obes (Lond).
  10. Chen LW, Tint MT, Fortier MV, Aris IM, Shek LP, Tan KH, Rajadurai VS, Gluckman PD, Chong YS, Godfrey KM, Kramer MS, Henry CJ, Yap F, Lee YS. 2017 Oct 12. Body composition measurement in young children using quantitative magnetic resonance: a comparison with air displacement plethysmography. Pediatr Obes. doi: 10.1111/ijpo.12250.

Professional Memberships

  • President, Asia Pacific Paediatric Endocrine Society (Nov 2020 to Nov 2022)
  • President, College of Paediatrics and Child Health, Academy of Medicine, Singapore (Aug 2021 to Jun 2023)



 

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