Care at NUH

Pharmacogenomics

2026/03/30

Right Drug • Right Dose • For You

Pharmacogenomics (PGx) helps us understand how your genes influence the way your body processes medications. As everyone’s genetic makeup is unique, the same medicine may work differently from one person to another. PGx testing allows doctors and pharmacists to choose medicines and doses that are safer and more effective for you.

What is Pharmacogenomics?

Pharmacogenomics is the study of how genetic differences affect your response to medication. These genetic differences influence:

  • How fast your body breaks down a medicine
  • How strong or weak the effect of a medicine may be
  • Your likelihood of experiencing side effects

Studies show that 99% of people carry at least one genetic variation that affects how they respond to medicines. This means nearly everyone can benefit from knowing their PGx profile.

Why Consider Pharmacogenomics?

PGx testing helps your care team:

  • Identify medicines that are safer and more effective for you
  • Reduce the chance of unwanted side effects
  • Avoid medications that may not work well for you
  • Tailor your prescriptions based on your genetics

Genes do not change over your lifetime, hence PGx results remain relevant whenever you need medication in the future.

How PGx Testing is Carried Out

You may be approached by a clinical research coordinator during a visit to any of the institutions under NUHS, i.e. NUH, AH, NTFGH, or NUP. If you would like to express interest directly, you can email: [email protected]

A simple overview of the testing process:

Your test results will not diagnose or treat any disease. They are used only to guide safer and more personalised medication choices.

Who Can Benefit from PGx Testing?

PGx may be especially helpful if:

  • You take several medications
  • You’ve had unexpected reactions to medicines before
  • You are starting a medication with known PGx guidance
  • You want your treatment to be as personalised as possible

As PGx helps prevent ineffective or harmful prescriptions, it may also help to reduce medical costs, improve medication outcomes, and lower the risk of side effects.

Our Team

The PGx programme at NUHS is supported by a multidisciplinary team acracross NUH, Alexandra Hospital, Ng Teng Fong General Hospital and National University Polyclinicsss NUH, Alexandra Hospital, Ng Teng Fong General Hospital and National University Polyclinics:

  • Physicians
  • PGx‑trained pharmacists
  • Researchers
  • Precision medicine specialists
How to Participate or Obtain Referral

For Patients 

Please write to [email protected] to express interest in PPGx participation. 

For Clinicians 

Kindly advise eligible patients to contact the study team at [email protected].

Resources
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National University Health System
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