Care at NUH

Cancer Genetics Clinic

2026/03/30

Hereditary cancers develop when a person inherits a genetic change (also called a mutation or variant) from one of their parents. These inherited changes account for about 5–10% of all cancers and may significantly increase a person’s lifetime risk of developing certain cancers.

Understanding whether cancer in your family may be hereditary can empower you and your loved ones to make informed decisions about screening, prevention, and treatment.

Our Services

Patients referred to our cancer genetics service receive personalised care that includes:

During a new consultation:

  • A review of your personal cancer history
  • A detailed discussion of your family history
  • A risk assessment for potential hereditary cancer syndromes

If a hereditary cancer syndrome is suspected, we offer:

  • Clear, supportive genetic education and counselling
  • Discussion of lifetime cancer risks associated with the suspected syndrome
  • Explanation of the benefits and limitations of genetic testing
  • Personalised screening recommendations for you and your family
  • Guidance on preventive options
  • Opportunities for research participation, when available

If you decide to proceed, blood can usually be taken on the same day.

How Does Genetic Testing Help?

Genetic testing can:

  • Identify whether your cancer was caused by an inherited gene change
  • Help guide treatment decisions specific to your cancer type
  • Provide insights about your future cancer risks
  • Support you and your healthcare team in planning preventive or early‑detection strategies
  • Help family members understand their inherited risks and seek screening early

Testing is performed using a simple blood sample by trained healthcare professionals.

Who Should Be Referred to Us?

You may benefit from genetic evaluation and counselling if you or your family members have experienced:

  • Cancer at a young age (e.g., breast cancer before age 50, colon cancer before age 50)
  • Multiple relatives with the same or related cancers (e.g., breast and ovarian cancer, colon and uterine cancer)
  • More than one primary cancer in the same individual
  • A known genetic mutation in the family
  • Rare tumours, such as male breast cancer, paraganglioma, or medullary thyroid cancer
  • Clinical features linked to inherited cancer syndromes, such as multiple colonic polyps

These patterns may suggest underlying hereditary cancer syndrome.

Our Team

Our cancer genetics team provides comprehensive clinical care, education, and support for patients and families. The service is led by:

Prof Lee Soo Chin
Senior Consultant

Adj A/Prof Samuel Ow
Senior Consultant

Dr Gloria Chan
Consultant

Dr Robert Walsh
Consultant

Dr Manavi Sachdeva
Associate Consultant

Cancer Genetics Counsellors
Ms Ong Pei Yi
Ms Vanessa Lim

Our team works together to support you through evaluation, testing, and personalised care planning.
Resources
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Location & Contact

National University Cancer Institute, Singapore (NCIS)

Medical Centre @ Level 10
5 Lower Kent Ridge Road
Singapore 119074

Opening Hours

Monday – Friday: 8.00am–5.30pm
Closed on Saturdays, Sundays & Public Holidays

Contact Us

Phone: +65 6773 7888
Email: [email protected]
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