The Division of Reproductive Endocrinology and Infertility stands as a cornerstone in the provision of advanced reproductive healthcare. Our team is dedicated to offering a wide range of services tailored to address various reproductive health concerns, including hormonal disorders, infertility, and other aspects of reproductive and climacteric medicine. We provide a patient-centred approach at every vital stage of a woman’s life – from adolescence to reproductive age, and all the way to menopause.
The Division offers a multidisciplinary approach to infertility management, considering both male and female factors that contribute to reproductive challenges. We offer a full range of fertility investigations and treatment options such as Intra-uterine Insemination (IUI), In-vitro Fertilisation (IVF), Intra-Cytoplasmic Sperm Injection (ICSI), Pre-implantation Genetic Testing (PGT) as well as embryo, oocyte, and sperm cryopreservation.
From 1 July 2023, women aged 21 to less than 38 years will have the option to freeze their eggs for non-medical reasons. For more information, click here.
In-vitro Fertilisation (IVF) is the most effective and one of the most widely used fertility treatments that offers hope to couples with reproductive challenges. It involves collecting eggs from the ovaries, fertilising an egg with sperm in the laboratory, and then transferring the resulting embryo into the womb.
IVF may be recommended for a range of fertility issues, including:
Patients undergoing IVF are supported by our team of Reproductive Medicine specialists, nurses, embryologists, and counsellors. All procedures required during an IVF cycle, including ovarian stimulation and monitoring, egg retrieval and embryo transfer, are performed on-site at our state-of-the-art facilities.
1. Ovarian stimulation
Fertility hormone medications are used to stimulate the ovaries to produce multiple mature eggs, maximising the chance of success. Throughout this phase, we monitor follicular development and hormone levels through transvaginal ultrasounds and blood tests every 2 to 3 days for about 10 to16 days.
2. Egg retrieval
Once the follicles are ready, we perform a minor transvaginal outpatient procedure to retrieve the eggs. This is done under general anaesthesia and typically takes about 30 minutes.
3. Fertilisation
The retrieved eggs are fertilised with sperm at our state-of-the-art laboratory. Depending on the sperm quality, we may use conventional insemination or intracytoplasmic sperm injection (ICSI) to fertilise the eggs.
4. Embryo development
Fertilised eggs are monitored as they develop into embryos over 3 to 5 days. Our embryologists assess each embryo daily to determine which are healthiest and most viable for transfer or for freezing.
5. Embryo transfer
A selected embryo is carefully transferred into the womb using a thin catheter. This is a gentle, minimally invasive procedure that typically does not require anaesthesia.
6. Pregnancy test
About 12 to14 days after the embryo transfer, a blood test to check for pregnancy is done at the Clinic for Human Reproduction (CHR). Our team will provide close support and guidance through the results, and offer advice on follow-up steps.
IVF can be a physically and emotionally intense process. Our dedicated team at the Clinic for Human Reproduction is committed to guiding you with compassion, transparency, and the highest standard of care. Your goals are our mission.
We offer three types of pre-implantation genetic testing (PGT).
Couples will be referred to a genetics specialist prior to pre-implantation genetic testing for proper counselling.
PGT-M is done with either spouse has a known inheritable condition. It is performed on embryos collected after IVF to screen for specific genetic conditions.
PGT-SR is done with either spouse has an abnormal chromosome number or structure that may increase the risk of a miscarriage or having a child with a chromosomal anomaly. It is performed by looking at the chromosome structure of the embryos collected after IVF.
In Singapore, PGT-A can only be performed in public healthcare institutions when any of the following criteria are met:
PGT-A identifies embryos with abnormal chromosome numbers. This helps the doctor choose which embryo to transfer and results in higher implantation rates and lower miscarriage rates.
This reproductive technique allows women to preserve their ability to have biological children in cases where fertility may be compromised due to illness, cancer treatment, or surgery. It involves freezing sperm, eggs, embryos, or ovarian tissue.
The patient must be referred by their primary cancer specialist to our fertility clinic. Upon review, a detailed assessment is done to begin fertility treatment soonest possible.
Subfertility Clinic
Located within Women's Clinic Jade (Former Clinic G)
Opening Hours
Mon - Thu: 8:30am to 6:00pm
Fri: 8:30am to 5:30pm
Sat, Sun & PH: Closed
Location
NUH Kent Ridge Wing
Zone C, Level 3
C03-02
Contact: [email protected]
Clinic for Human Reproduction (CHR)
The Clinic for Human Reproduction was established to address fertility issues in couples. Since its inception, we have made key discoveries that are vital to the advancement in the field of assisted reproduction.
Women's Clinic - Emerald/Ruby
