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Doctor Details

2024/01/25
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Dr Ryan Leow Zi Liang

Photo of Dr Ryan Leow Zi Liang

Designations:

  • Associate Consultant, Department of Cardiology, National University Heart Centre, Singapore

Qualifications:

MBBS (Honours) (NUS), MRCP (UK), M. Med (Internal Medicine)

Specialties/Sub-specialties:

Cardiology

Clinical Disciplines/Programmes:

Cardiac Critical Care, Cardiac Imaging (Echocardiography), Cardiology (Heart), General Cardiology, Heart Valve Disease

Special Interests:

Echocardiography, Transoesophageal Echocardiography, Valvular Heart Disease, Critical Care Cardiology

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Biosketch

Dr. Ryan Leow obtained his undergraduate medical degree from the Yong Loo Lin School of Medicine, National University of Singapore, having placed on the Dean's List for all five years of the course and having placed first in the final undergraduate examinations with firsts in both Medicine and Surgery. He was awarded seven University academic awards, was conferred his undergraduate medical degree with Honours, and was the Valedictorian of his graduating class.

Dr. Leow undertook Internal Medicine training and then Cardiology specialisation with the National University Health System. He presently practices at the National University Hospital and Ng Teng Fong General Hospital, with clinical interests in cardiac critical care as well as echocardiography. 

His research interests lie in valvular heart diseases as well as echocardiography with multiple publications in these fields. He frequently presents his work in local and international conferences, where his presentations have won research awards including two Young Investigator Awards.

Dr. Leow's other interests include medical education and he teaches under the clinical faculty scheme with NUS. He actively tutors undergraduates and is a sought-after tutor for junior medical residents preparing for post-graduate examinations. He has received awards from NUS and the NUHS recognising these educational contributions. 

Awards

  • Singapore LIVE 2025 Conference
    Best Session Clinical Case Presentation Award
  • Singapore Cardiac Society Annual Scientific Meeting 2024
    Best Session Oral Presentation Award

  • Japanese Circulation Society Annual Scientific Meeting 2022 
    Third Prize

  • American College of Cardiology Asia - Singapore Cardiac Society Annual Scientific Meeting 2021
    Young Investigator Award - First Prize

  • ASEAN Federation of Cardiology Congress 2021
    Young Investigator Award - First Prize

  • Good Tutor Faculty Recognition Award
    Department of Medicine, NUH

  • Best Residency Tutor Award
    Department of Medicine, NUH

Journals & Publications

  1. Leow R, Chan MW, Li TY, Kong WK, Poh KK, Kuntjoro I, Sia CH, Yeo TC. . Clinical Characteristics, Hemodynamic Profile, and Outcomes in Patients With Low-Gradient and High-Gradient Severe Mitral Stenosis: Influence of Flow Status. J Am Heart Assoc. 2025 Oct 21;14(20):e041884. doi: 10.1161/JAHA.125.041884. Epub 2025 Oct 9. PMID: 41065245.

  2. Leow R, Sia CH, Li TY, Chan MW, Lim EH, Ng LMJ, Yeo TC, Poh KK, Tan HC, Kong WK. Clinical and echocardiographic differences between rheumatic and degenerative mitral stenosis. Ann Acad Med Singap. 2025 Apr 4;54(4):227-234. doi: 10.47102/annals-acadmedsg.2024351. PMID: 40324890.

  3. Leow R, Li TY, Chan MW, Kong WK, Poh KK, Kuntjoro I, Sia CH, Yeo TC. Differentiation of the severity of rheumatic mitral stenosis using dimensionless index and its association with outcomes. Int J Cardiol Cardiovasc Risk Prev. 2025 Jan 7;24:200366. doi: 10.1016/j.ijcrp.2025.200366. PMID: 39882191; PMCID: PMC11774812.

  4. Leow R, Li TY, Chan MW, Kong WKF, Chan SP, Poh KK, Kuntjoro I, Sia CH, Yeo TC. Association of Yeo's index with clinical outcomes in rheumatic mitral stenosis. Sci Rep. 2024 Nov 27;14(1):29417. doi: 10.1038/s41598-024-76534-3. PMID: 39592698; PMCID: PMC11599848.

  5. Li T, Leow R, Chan MW, Kong WKF, Kuntjoro I, Poh KK, Sia CH, Yeo TC. Impact of Net Atrioventricular Compli-ance on Mitral Valve Area Assessment-A Perspective Considering Three-Dimensional Mitral Valve Area by Transesophageal Echocardiography. Diagnostics (Basel). 2024 Jul 24;14(15):1595. doi: 10.3390/diagnostics14151595. PMID: 39125471; PMCID: PMC11311854.

  6. Li T, Leow R, Chan MW, Kong WKF, Kuntjoro I, Poh KK, Sia CH, Yeo TC. Combining 2D Planimetry and Yeo's Index Can Help Accurately Identify Patients with Severe Rheumatic Mitral Stenosis-A Perspective from a 3D Assessment Using Transoesophageal Echocardiography. Diagnostics (Basel). 2024 Jul 5;14(13):1440. doi: 10.3390/diagnostics14131440. PMID: 39001329; PMCID: PMC11240934.

  7. Leow R, Li TY, Kong WKF, Poh KK, Kuntjoro I, Sia CH, Yeo TC. Validation of Yeo's index in assessing severity of rheumatic mitral stenosis in mixed valve lesions. Int J Cardiol Heart Vasc. 2024 Jun 15;53:101447. doi: 10.1016/j.ijcha.2024.101447. PMID: 38979528; PMCID: PMC11228633. 

  8. Leow R, Kong WKF, Li TY, Poh KK, Sia CH, Yeo TC. Yeo's index: A novel index that combines anatomic and haemodynamic assessment of the severity of mitral stenosis. Int J Cardiol. 2023 Dec 1;392:131350. doi: 10.1016/j.ijcard.2023.131350. Epub 2023 Sep 7. PMID: 37689399.

  9. Yedidya I, Butcher SC, Stassen J, van der Bijl P, Ngiam JN, Chew NWS, Sia CH, Leow R, Li TY, Kong WKF, Poh KK, Kornowski R, Marsan NA, Delgado V, Bax JJ. Prognostic value of left atrial volume index in de-generative mitral stenosis. Int J Cardiovasc Imaging. 2022 Dec;38(12):2687-2693. doi: 10.1007/s10554-022-02691-z. Epub 2022 Jul 18. PMID: 36445660; PMCID: PMC9708792.

  10. Ngiam JN, Chew NWS, Sim MY, Liong TS, Li TYW, Leow R, Sia CH, Loh PH, Wong RCC, Yeo TC, Poh KK, Kong WKF. Clinical and echocardiographic characteristics associated with the development of infective endo-carditis in patients with significant mitral stenosis. Echocardiography. Epub 2021 Dec 20. https://doi.org/10.1111/echo.15283.

2026/03/19
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