A/Prof Su graduated with MB BChir PhD from the University of Cambridge (UK) and joined Institute of Molecular and Cell Biology (IMCB) in 2016 as a clinician-scientist. She balances her time leading a broad retinal research programme as Executive Director at IMCB while providing clinical leadership as Senior Consultant Vitreo-Retinal Surgeon with the Department of Ophthalmology at the National University Hospital (NUH). A/Prof Su also holds joint appointments as Research Director at the Department of Ophthalmology, National University of Singapore (NUS), and Clinician-Scientist at the Singapore Eye Research Institute (SERI).
Her research focuses on harnessing biomaterial, regenerative stem-cell, and nucleic acid technologies for the treatment of age-related retinal degenerative disease. Her work has been published in, inter alia, Nature Biomedical Engineering, Nature Communications, Lancet Global Health, The Proceedings of National Academy of Sciences (PNAS), and Advanced Materials. She has secured over SGD$25 million in competitive research grants, and received numerous prestigious accolades both locally and internationally. These include the Asia-Pacific Academy of Ophthalmology’s Young Ophthalmologist Award (2019 and 2020), the Asia-Pacific Vitreo-Retinal Society Leadership Development Program Gold Award (2020), Junior Chamber International Ten Outstanding Young People Gold Award for Medical Innovation (2021), the Susan Lim Outstanding Stem Cell Young Investigator Award (2022) and the National Medical Research Council Clinician Scientist Award (2022). In 2021, she was accepted into the prestigious international membership of The Macular Society.
Passionate about clinical translation of research, A/Prof Su holds several patents and co-founded an ISO 13485 (Medical Device Quality System) accredited spin-off company, Vitreogel Innovations, focused on developing the next generation of vitreous substitutes. Beyond research, A/Prof Su is committed to people development and has mentored numerous clinician-scientists as she served as Deputy Director of the Clinician-Scientist Academy, National University Health System (NUHS) from 2022 to 2024.
1.Liu Z, Liow SS, Lai SL, Alli-Shaik A, Holder GE, Parikh BH, Krishnakumar S, Li Z, Tan MJ, Gunaratne J, Barathi VA, Hunziker W, Lakshminarayanan R, Tan CWT, Chee CK, Zhao P, Lingam G**, Loh XJ*, Xinyi Su*. Retinal-detachment repair and vitreous-like body reformation via a thermogelling polymer endotamponade. Nature Biomed Eng. 2019 Aug;3(8):598-610. (PMID 30962587). IF:29.23]
2. Bhav Harshad Parikh, Zengping Liu, …Timothy A. Blenkinsop, Walter Hunziker, Gopal Lingam, Xian Jun Loh*, Xinyi Su* A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway. Nature Communications (IF: 17.69)
3. Xinxin Zhao, Ivan Seah, Kun Xue, Wendy Wong, Queenie Shu Woon Tan, Eloise Xiao Ma, Qianyu Lin, Jason Y.C. Lim, Zengping Liu, Bhav Harshad Parikh, Joel Weijia Lai, Binxia Yang, Kim Chi Tran, Veluchamy Amutha Barathi, Kang Hao Cheong, Walter Hunziker, Xinyi Su*, Xian Jun Loh* Anti-Angiogenic Nanomicelles for the Topical Delivery of Aflibercept to Treat Retinal Neovascular Disease. Advanced Materials 2021 Nov 2;e2108360. doi: 10.1002/adma.202108360. (PMID 34726299) [IF: 32.09]
4. Liu Z, Parikh H, Tan Q.S.W, Wong D.S.L. Ong K.H., Yu W, Seah J.Y, Holder G.E, Hunziker W, Tan G.W.S, Barathi V.A., Lingam G, Stanzel B.V, Blenkinsop T.A.*, Xinyi Su* Surgical Transplantation of Human RPE Stem Cell-Derived RPE Monolayer in a Non- Human Primates with Immunosuppression. Stem Cell Reports 2021 (Feb)9;16(2):237-251. (PMID 33450191) (Featured on cover page of issue) [IF:7.765]
5. Swathi Lingam, Zengping Liu, Binxia Yang, Wendy Wong, Bhav Harshad Parikh, Jun Yi Ong, Debbie Goh, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Gavin S W Tan, Graham E Holder, Kakkad Regha, Veluchamy Amutha Barathi, Walter Hunziker, Gopal Lingam, Xianmin Zeng, Xinyi Su* cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates. Stem Cell Res Ther 2021 Aug 19;12(1):463 (PMID 34412697). IF:6.832
