Care at NUH

Doctor Details

Find a Doctor
Doctor Detail

Dr Samantha Yang Peiling

Photo of Dr Samantha Yang Peiling


  • Senior Consultant, Division of Endocrinology, Department of Medicine, National University Hospital
  • Senior Consultant, National University Cancer Institute, Singapore
  • Assistant Professor, Yong Loo Lin School of Medicine, National University of Singapore


MBBS (S'pore), MRCP (UK), M Med (Int Med)



Clinical Disciplines/Programmes:


Special Interests:

Thyroid nodule molecular diagnostics, Thyroid cancer treatment and surveillance, Genetics, Metabolic bone disease


Dr Yang obtained her medical degree (MBBS) and Masters of Medicine from the National University of Singapore and the Royal College of Physicians, United Kingdom [MRCP (UK)]. She received her training in Endocrinology at National University Hospital, Singapore. She then completed a thyroid cancer fellowship at Memorial Sloan Kettering Cancer Centre in New York, United States, where she was involved in clinical research and clinical work pertaining to thyroid nodule and thyroid cancer.

Her interests are in the evaluation of patients with thyroid nodules, and the treatment and surveillance of thyroid cancer patients. She is involved in molecular studies for the evaluation of patients with thyroid nodules, and re-differentiation therapy for radioactive iodine-refractory thyroid cancer patients.

Education and Fellowships
MBBS (S'pore), MRCP (UK), M Med (Int Med), Endocrinology Fellowship Singapore (Joint committee on Specialist Training), Thyroid Cancer Fellowship (Memorial Sloan Kettering Cancer Centre, United States), Endocrine Certification in Neck Ultrasound (American Association of Clinical Endocrinologists), Master of Clinical Investigation (S'pore)


  • National Medical Research Council Research Fellowship 2019-2023
  • NUHS Clinician Scientist Program Award 2015-2019
  • Endocrine & Metabolic Society of Singapore Research Funding Award 2015-2018

Journals & Publications

  1. David L. Steward, Sally E. Carty, Rebecca S. Sippel, Samantha Peiling Yang, Julie A. Sosa, Jennifer A. Sipos, James J. Figge, Susan Mandel, Bryan R. Haugen, Kenneth D. Burman, Zubair W. Baloch, Ricardo V. Lloyd, Raja R. Seethala, William E. Gooding, Simion I. Chiosea, Cristiane Gomes-Lima, Robert L. Ferris, Jessica M. Folek, Raheela A. Khawaja, Priya Kundra, Kwok Seng Loh, Carrie B. Marshall, Sarah Mayson, Kelly L. McCoy, Min En Nga, Kee Yuan Ngiam, Marina N. Nikiforova, Jennifer L. Poehls, Matthew D. Ringel, Huaitao Yang, Linwah Yip, Yuri E. Nikiforov. Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology A Prospective Blinded Multicenter Study. JAMA Oncology 2019 Feb 1;5(2):204-212 (IF 16.56).
  2. Goh X, Lum J, Yang SP, Chionh SB, Koay E, Chiu L, Parameswaran R, Ngiam KY, Loh TKS, Nga ME, Lim CM. BRAF mutation in Papillary Thyroid cancer - prevalence and clinical correlation in a Southeast Asian cohort. Clin Otolaryngol 2018 Oct 8.
  3. Samantha Peiling Yang, Joanne Ngeow. Familial non-medullary thyroid cancer- unraveling the genetic maze. Endocrine-related cancer. 2016 Dec;23(12):R577-R595.
  4. Samantha Peiling Yang, Adriane M. Bach, R. Michael Tuttle, Stephanie Fish. Continued routine screening with serial neck ultrasound is more likely to identify false positive abnormalities than clinically significant disease in the surveillance of intermediate risk papillary thyroid cancer patients classified as having no evidence of disease on the initial follow-up evaluation. Journal of Clinical Endocrinology & Metabolism 2015;100(4):1561-1567.
  5. Samantha Peiling Yang, Ariadne M. Bach, R. Michael Tuttle, and Stephanie A. Fish. Serial neck ultrasound is more likely to identify false positive abnormalities than clinically significant disease in low risk papillary thyroid cancer patients. Endocrine Practice: December 2015;21(12):1372-1379.
  6. Samantha Peiling Yang, Lee Suat Ying, Stephanie Saw, R. Michael Tuttle, Kavita Venkataraman, and Chia Su-Ynn. Practical barriers to implementation of thyroid cancer guidelines in the Asia-Pacific region. Endocrine Practice: November 2015;21( 11):1255-1268.
  7. Denise P Momesso, Fernanda Vaisman, Samantha P Yang, Bulzico DA, Rossana Corbo,Mario Vaisman, R Michael Tuttle. Dynamic risk stratification in differentiated thyroid cancer patients treated without radioactive iodine. The Journal of Clinical Endocrinology & Metabolism 2016;101(7):2692-700.
  8. Samantha, Peiling Yang, Tae Won Kim, Patrick J. Boland, Azeez Farooki. Retrospective Review of Atypical Femoral Fracture in Metastatic Bone Disease Patients Receiving Denosumab Therapy. The Oncologist 2017;22(4):438-444.

Professional Memberships

  • Endocrine & Metabolic Society of Singapore- past committee 2009
  • American Thyroid Association

Last updated on
Best viewed with Chrome 79.0, Edge 112.0, Firefox 61.0, Safari 11
National University Health System
  • National University Hospital
  • Ng Teng Fong General Hospital
  • Alexandra Hospital
  • Jurong Community Hospital
  • National University Polyclinics
  • Jurong Medical Centre
  • National University Cancer Institute, Singapore
  • National University Heart Centre, Singapore
  • National University Centre for Oral Health, Singapore
  • NUHS Diagnostics
  • NUHS Pharmacy
  • Yong Loo Lin School of Medicine
  • Faculty of Dentistry
  • Saw Swee Hock School of Public Health
Back to Top