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Prof Lynette Shek

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  • Senior Consultant, Division of Paediatric Allergy, Immunology & Rheumatology, Department of Paediatrics, Khoo Teck Puat - National University Children's Medical Institute, National University Hospital
  • Professor, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore


MBBS (Hons) (S'pore), MRCP (Paeds) (UK), MRCPCH (UK), FAAAI


Paediatric Medicine

Clinical Disciplines/Programmes:

Paediatric Allergy & Immunology (Allergy & Immune System Disorders)

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Professor Lynette Shek is currently a Senior Consultant of the Division of Paediatric Allergy, Immunology and Rheumatology at the National University Hospital (NUH).

She obtained her basic medical degree from the National University of Singapore (NUS) with honours in 1994 and received her paediatric training at NUH from 1996 to 2001. She attained her postgraduate paediatric degree in 1997. She was accredited as a specialist in Paediatric Medicine by the Ministry of Health, Singapore in 2001 and became a Fellow of the Academy of Medicine, Singapore in 2004. She has been a member of the Faculty of Medicine, Department of Paediatrics since 1996 and was promoted to Associate Professor in 2007, and subsequently, Professor in 2019.

Her specialist training in allergy was undertaken from 2002 to 2003 at Mt Sinai School of Medicine, New York. There, Prof Shek trained under Professor Hugh Sampson, a world-renowned expert in the field of allergy. She also spent some time under the tutelage of Professor Thomas Lehman, Chief, Division of Paediatric Rheumatology, at the Hospital for Special Surgery, New York. 

Since her return in 2004, she has been practising as a paediatrician in NUH. Her clinical practice involves all areas of general paediatrics with special interests in the fields of allergy, immunodeficiency and rheumatology. She sees adult patients with allergy and immunodeficiency in NUH as well. 

Prof Shek is a Fellow of the American Academy of Allergy, Asthma and Immunology. She is also actively involved in research. She is a member of both the Asthma & Allergy Research Programme and the Human & Molecular Research Programme at NUS. She has published her work on allergy and rheumatology in numerous medical journals.
She won the NUH Young Doctor's Award in 1999 for her research on the genetics of asthma and atopy in local Chinese children. She was the youngest recipient of the National Medical Research Council-Biomedical Research Council (NMRC-BMRC) Clinician Scientist Investigator Award in 2005. In 2011, she won the Clinician Scientist (Investigator) Award for her work in early childhood rhinitis at the NMRC Awards Ceremony.

Journals & Publications

  1. Jafar NK, Tham EK, Eng DZ, Goh DY, Lee YS, Shek LP, . . . Gusto Study Group (2017). The association between chronotype and sleep problems in preschool children. Sleep Medicine, 30:240-244. doi: 10.1016/j.sleep.2016.11.015
  2. Wen DJ, Poh JS, Ni SN, Chong YS, Chen H, Shek LP, . . . Qiu A (2017). Influences of prenatal and postnatal maternal depression on amygdala volume and microstructure in young children. Translational Psychiatry, 7(4):e1103. doi: 10.1038/tp.2017.74
  3. Loo EX, Goh A, Aris IBM, Teoh OH, Shek LP, Lee BW, . . . Lee YS (2017). Effects of infant weight gain on subsequent allergic outcomes in the first 3 years of life. BMC Pediatrics, 17(1):134. doi: 10.1186/s12887-017-0890-0
  4. Loo EXL, Sim JZT, Loy SL, Goh A, Chan YH, Shek LP, . . . Ang SB (2017). Associations between caesarean delivery and allergic outcomes: Results from the GUSTO study. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma & Immunology, 118(5):636-638. doi: 10.1016/j.anai.2017.02.021
  5. Thalayasingam M, Loo EX, Tan MM, Bever HV, Shek LP (2015). A review of oral food challenges in children presenting to a single tertiary centre with perceived or true food allergies. Singapore Medical Journal, 56(11):622-5. doi: 10.11622/smedj.2015171

Professional Memberships

  • Fellow of the American Academy of Allergy, Asthma and Immunology
  • Member of the Asthma & Allergy Research Programme, NUS
  • Member of the Human & Molecular Research Programme, NUS

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