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Doctor Details

2024/01/25
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Asst Prof Cyrus Ho

Photo of Asst Prof Cyrus Ho

Designations:

  • Senior Consultant, Department of Psychological Medicine, National University Hospital
  • Assistant Professor, Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore

Qualifications:

MBBS (S’pore), Dip (Cl Psy) (RCP&S, Ire), FRCPsych (UK), FRCP (Edin), Grad Dip Acupuncture (S’pore), MSc (Research) (S’pore), MSc (App Neurosci) (UK), PhD (S’pore), FAMS (Psy) (S’pore), IFAPA (USA)

Specialties/Sub-specialties:

Psychiatry

Clinical Disciplines/Programmes:

General Adult Psychiatry

Special Interests:

Mood disorders, Neuropsychiatry

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Biosketch

Dr Cyrus Ho manages psychiatric conditions across the age continuum from adolescence to old age. He is interested in interfacing between medicine and psychiatry, complex mood disorders, neuropsychiatry and public mental health.

He studied medicine at NUS and subsequently obtained a Master of Science in Research from NUS for his work on neuroimaging in depressed and chronic pain patients, a Master of Science in Applied Neuroscience (Distinction) from King’s College London and a doctorate from NUS for his research work on improving the diagnostic accuracy of depression using multimodal biomarkers. He also underwent neuropsychiatry training at the Montreal Neurological Hospital in Canada and the Royal Melbourne Neuropsychiatry Unit in Australia under the Ministry of Health (MOH) Health Manpower Development Plan award, where he enhanced his expertise in the diagnosis and management of patients with complex neurological and psychiatric needs. He was conferred a Fellowship of the Royal College of Psychiatrists (UK), the Royal College of Physicians of Edinburgh, the American Psychiatric Association and the Singapore Academy of Medicine for his contribution to Psychiatry.

Being an avid researcher, Dr Ho has published more than 390 academic papers in international peer-reviewed journals, including The Lancet, JAMA Pediatrics, Annals of Internal Medicine, Autoimmunity Reviews and Brain, Behavior and Immunity. He is also the Section Editor for the British Journal of Psychiatry. Clarivate Analytics (Web of Science) has recognised him as one of the most highly cited researchers in the world for his contributions to cross-field research from 2021 to 2023, and in Neuroscience and Behavioural Rresearch in 2024.

He teaches at the undergraduate and postgraduate levels. He currently serves as the NUS Psychiatry Undergraduate Education Director and is the Assistant Dean (Student Life and Wellbeing) of the NUS Graduate School. He is also an examiner for the postgraduate clinical examination conducted by the Royal College of Psychiatrists, UK. His recognition in education is exemplified by the several teaching awards he has received, including the NUS Annual Teaching Excellence Award, NUS Annual Digital Education Award, Yong Loo Lin School of Medicine Educator of the Year, Yong Loo Lin School of Medicine Digital Education Award, and Dean's Award for Teaching Excellence. He has co-authored six postgraduate guidebooks published by Cambridge University Press and Taylor & Francis and the Mastering Psychiatry Textbook, a popular reference book used by Singapore medical students during their clinical postings.

Always interested in pushing the boundaries of research to effect innovative healthcare, Dr Ho welcomes clinical and research collaboration locally and internationally.

Awards


  • Yong Loo Lin School of Medicine Educator of the Year Award (2025)
  • NUS Annual Teaching Excellence Award (2025)
  • Dean's Award for Teaching Excellence, NUS (2025, 2023, 2021,2020, 2018)
  • Clarivate Highly Cited Researcher - Neuroscience and Behaviour (2024)
  • NMRC Transition Award (2023)
  • NUS Annual Digital Education Award (2023)
  • Yong Loo Lin School of Medicine Digital Education Award (2023)
  • Clarivate Highly Cited Researcher - Cross Field (2023, 2022, 2021)
  • NUHS Teaching Excellence Award (2021)
  • Japanese Society of Psychiatry and Neurology Fellowship Award (2020)
  • NUS Medicine Fortitude Award (2020)
  • MOH Health Manpower Development Plan (HMDP) Award (2018)

Journals & Publications

  1. Ho CSH, Wang J, Tay GWN, et al. Application of functional near-infrared spectroscopy and machine learning to predict treatment response after six months in major depressive disorder. Transl Psychiatry. 2025 Jan 11;15(1):7. [IF 6.2]
  2. Ho CSH, Wang J, Tay GWN, et al. Interpretable deep learning model for major depressive disorder assessment based on functional near-infrared spectroscopy. Asian J Psychiatr. 2024 Jan 3;92:103901. [IF 4.5]
  3. Lee ARYB, Low CE,…, Ho CSH. Lifetime Burden of Psychological Symptoms, Disorders, and Suicide Due to Cancer in Childhood, Adolescent, and Young Adult Years: A Systematic Review and Meta-analysis. JAMA Pediatr. 2023 Jun 22:e232168. [IF 18]
  4. Li T, Yuan L, Zhao Y,…, Ho CSH. Blocking osteopontin expression attenuates neuroinflammation and mitigates LPS-induced depressive-like behavior in mice. J Affect Disord. 2023 Feb 24:S0165-0327(23)00273-2. [IF 4.9]
  5. Ho CSH, Tay GWN, Wee HN, et al. The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression Severity. International Journal of Molecular Sciences. 2023 Jan 23; 24(3):2231. [IF 4.9]
  6. Ho CSH, Soh MWT, Tay GWN. The diagnostic utility of miRNA and elucidation of pathological mechanisms in major depressive disorder. Compr Psychiatry. 2022 Dec 23;121:152363. [IF 4.2]
  7. Lam RW, Wong HK, Kumarsing RA,…, Ho CS. Fluoxetine improves bone microarchitecture and mechanical properties in rodents undergoing chronic mild stress - an animal model of depression. Transl Psychiatry. 2022 Aug 20;12(1):339. [IF 6.2]
  8. Li Z, McIntyre RS, Husain SF,…, Ho CS, Chen N. Identifying neuroimaging biomarkers of major depressive disorder from cortical hemodynamic responses using machine learning approaches. EBioMedicine. 2022 Apr 28;79:104027. [IF 10.8]
  9. Ho CS, Chan YL, Tan TW, et al. Improving the diagnostic accuracy for major depressive disorder using machine learning algorithms integrating clinical and near-infrared spectroscopy data. J Psychiatr Res. 2022 Jan 12;147:194-202. [IF 3.2]
  10. Li H, Xiang Y, Zhu Z,…, Ho CSH. Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat. J Neuroinflammation. 2021 Nov 4;18(1):254. [IF 10.1]

Professional Memberships

  • Fellow, Royal College of Physicians of Edinburgh
  • Fellow, Royal College of Psychiatrists, United Kingdom
  • Fellow (Psychiatry), Academy of Medicine Singapore
  • International Fellow, American Psychiatric Association, United States
  • Fellow, International Society for Affective Disorders
  • Member, American Neuropsychiatric Association, United States
  • Member, Academy of Consultation-Liaison Psychiatry, United States

2026/05/21
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