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2024/01/25
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Dr Charmaine Chai

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Designations:

  • Senior Consultant, Department of Ophthalmology, National University Hospital
  • Senior Consultant, Division of Ophthalmology, Alexandra Hospital
  • Assistant Professor, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore

Qualifications:

MBBS (S'pore), MMed (Ophth), FAMS

Specialties/Sub-specialties:

Ophthalmology

Clinical Disciplines/Programmes:

Cataract, Cornea, General Ophthalmology, Refractive Surgery

Special Interests:

Cataract, Myopia, Cornea Conditions, Fuchs Endothelial Dystrophy, Keratoconus    

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Biosketch

Dr Charmaine Chai is a Senior Consultant in the Department of Ophthalmology at the National University Hospital (NUH), where she also serves as Director of Clinical Services. She also sees patients at the Eye Surgery Centre, Alexandra Hospital.
 
Dr Chai graduated from the National University of Singapore (NUS), achieving the distinction of winning the Gold Medal and Book Prize in Ophthalmology. She obtained her Master of Medicine in Ophthalmology in 2014 and completed her residency training at NUH. She subsequently pursued fellowship training in Cornea and External Diseases and is accredited to perform various types of corneal transplants locally. Her clinical expertise encompasses Corneal and External Diseases as well as Cataract and Laser Refractive Surgery. As an experienced cataract surgeon, she performs a comprehensive range of cataract surgeries, including femtosecond laser-assisted cataract surgery, and is proficient in the use of various types of intraocular lenses available. She also performs a range of laser refractive surgery, including SMILE, LASIK and surface ablation treatments.
 
Driven by her passion in advancing patient care, Dr Chai actively contributes to both clinical research and medical innovation. She holds a patent for the development of a novel device for the management of compliance to eye drop medications. Her scholarly contributions include several publications and book chapters in the field, and she has presented her work at international conferences.
 
Having benefitted from excellent mentorship throughout her career, Dr Chai is passionate about educating the next generation of medical professionals. She is actively involved in both undergraduate and postgraduate teaching, mentoring medical students and specialists-in-training. She serves as a member of the Core Faculty of the NUHS Residency Programme and holds clinical tutor positions at both NUS Yong Loo Lin School of Medicine and Nanyang Technological University Lee Kong Chian School of Medicine.
 
She previously served as the Patient Safety Officer for the Department for several years before taking on her current role as Director of Clinical Services. In recognition of her outstanding contributions to the advancement of clinical ophthalmology, Dr Chai received the Meritorious Service Award at the Eye and Vision Health Awards Singapore 2024.

Awards

2024 - Meritorious Service Award at the Eye and Vision Health Awards Singapore

Journals & Publications

  1. Loke WT, Yew SME, Lim ZW, Lim BX, Chai C, Koh VTC, Chen DZ, Tham YC. Co-Management of Post-Cataract Surgery Patients Between Ophthalmologists and Optometrists: A Scoping Review. Ophthalmic Epidemiol. 2025 Nov 28:1-12. doi: 10.1080/09286586.2025.2587607. PMID: 41316717.
  2. Yeo LYX, Tan CYM, Allen JW, Chai C, Othman KB, Tham YC, Koh VTC, Savulescu J. Innovative care models: Expanding nurses' and optometrists' roles in ophthalmology. Nurs Ethics. 2025 Mar 12:9697330251317670. doi: 10.1177/09697330251317670. PMID: 40072479.
  3. Wu D, Chan KE, Lim BXH, Lim DK, Wong WM, Chai C, Manotosh R, Lim CHL. Management of corneal neovascularization: Current and emerging therapeutic approaches. Indian J Ophthalmol. 2024 May 1;72(Suppl 3):S354-S371. doi: 10.4103/IJO.IJO_3043_23. Epub 2024 Apr 20. PMID: 38648452.
  4. Wei Wei DY, Shen L, Manotosh R, Wee Tien AT, Hui-Chen CC. Relationship between Postoperative Intraocular Pressure and Refractive Outcomes in Patients after Deep Anterior Lamellar Keratoplasty. J Curr Ophthalmol. 2022 Apr 16;34(1):30-36. doi: 10.4103/joco.joco_211_21. PMID: 35620381; PMCID: PMC9128438.
  5. Yong WWD, Shen L, Manotosh R, Tan WTAM, Chai HCC. Impact of fibrin glue versus suture closure on double-headed pterygia in Asian eyes - a 7-year study in a tertiary institution. Ann Med. 2021 Dec;53(1):448-455. doi: 10.1080/07853890.2021.1901304. PMID: 33733974.
  6. Chen DZ, Chai C, Tan A, Ray M. Microbial patterns of Acanthamoeba keratitis at a Singapore ophthalmic referral hospital: A 5-year retrospective observational study. Ann Acad Med Singap. 2021 Jun;50(6):494-496. doi: 10.47102/annals-acadmedsg.2020507. PMID: 34195759.
  7. Yien L, Yanlong W, Chai C, Ching-Chiuan Y, Ho Y, Chuan ET, et al. The Effect of Patient Education and Telemedicine Reminders on Adherence to Eyedrops for Glaucoma. Ophthalmology Glaucoma. 2020. Pubmed PMID: 32980041
  8. Hernstadt DJ, Chai C, Tan A, Manotosh R. Three-year outcomes of Descemet's stripping endothelial keratoplasty in eyes with pre-existing glaucoma drainage devices. Can J Ophthalmol. 2019 Oct;54(5):577-584. doi:10.1016/j.jcjo.2018.12.012. Epub 2019 Feb 25. PubMed PMID: 31564348.
  9. Yong WWD, Chai HC, Shen L, Manotosh R, Anna Tan WT. Comparing Outcomes of Phacoemulsification With Femtosecond Laser-Assisted Cataract Surgery in Patients With Fuchs Endothelial Dystrophy. Am J Ophthalmol. 2018 Dec;196:173-180. doi:10.1016/j.ajo.2018.08.006. Epub 2018 Aug 8. PubMed PMID: 30098347.
  10. Ho D, Chai C, Lin H, Htoon HM, Tan AM, Manotosh R, Tan D. Optical and Tectonic Corneal Transplant Outcomes in a Tertiary Hospital in Singapore, within the Singapore Corneal Transplant Registry. Ann Acad Med Singapore. 2018 Mar;47(3):92-100. PMID: 29679087.

Professional Memberships

  • Fellow, Academy of Medicine, Singapore
  • Member, Asia Corneal Society
  • Singapore Medical Association
  • Asia-Pacific Ophthalmic Trauma Society (APOTS)

2026/04/27
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