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A/Prof Shridhar Iyer

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  • Senior Consultant, Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, National University Hospital
  • Senior Consultant, Division of Surgical Oncology, National University Cancer Institute, Singapore
  • Associate Professor, Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore
  • Senior Consultant, Adult Liver Transplantation Programme, National University Centre for Organ Transplantation, National University Hospital


MBBS (India), MS (India), FRCS (UK), FAMS (S'pore), MBA (S'pore)


General Surgery

Clinical Disciplines/Programmes:

Adult Liver Transplantation Programme, Chronic Programme (Live Better), FAST Programme (Get Better), Hepatobiliary & Pancreatic Surgery, Hepato-Pancreato-Biliary Surgery & Liver Transplantation, Organ Transplantation, Surgery, Surgical Oncology


"The liver is an enigmatic organ with over 500 functions and has a unique ability to regenerate, which allows removal of large parts of the organ in cancers and makes it possible to perform living donor liver transplant.  A lifetime is not enough to understand the organ and I am privileged to be a part of the community which advances the science." 
Early in his career in medicine, A/Prof Shridhar found his calling in the operating room. Surgery – for all its challenges and complexities, high pressure and exacting demands – is a state in which he finds himself at his best. Requiring intense concentration and focus, A/Prof Shridhar often finds himself in an immersive state of flow -- a state of mind described by renowned psychologist, the late Mihaly Csikszentmihalyi, as a phase of genuine satisfaction and the secret to happiness. 

A/Prof Shridhar graduated from Grant Medical College, Bombay University, India in 1994. He then underwent training in Surgical Oncology at the Tata Memorial Hospital; Mumbai and was admitted as a Fellow to the Royal College of Surgeons of Edinburgh, UK, in 1999. He completed his Advanced Specialty training in General Surgery at the National University Hospital in 2005 and admitted as a Fellow to the College of Surgeons, Academy of Medicine of Singapore. 
As a recipient of the Human Manpower Development Programme (HMDP) scholarship in 2006, A/Prof Shridhar went to pursue a Fellowship in Liver surgery and Liver transplantation at the Chang Gung Memorial Hospital, Taiwan. 
Today he is a Senior Consultant, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Co-Director of the National University Centre for Organ Transplantation (NUCOT), and Surgical Director and Senior Consultant in the Adult Liver Transplant Programme, NUCOT, at National University Hospital (NUH). He has over 15 years' experience in hepatobiliary and pancreatic surgery and liver transplantation.

Leading the way in liver surgery

In his role as a leader and innovator in the field, A/Prof Shridhar has developed enhanced clinical pathways and protocols for patients undergoing liver transplantation. He has also contributed actively to the development of Adult Living Donor Liver transplant programme and Donor Surgery for Paediatric Living Donor Liver Transplant at the NUH. 
A/Prof Shridhar has also led several quality improvement projects in the hospital in the area of bettering the outcomes of hepatobiliary and pancreatic surgery. These include improved processes to reduce the length of stay and driving more efficient discharge processes.These efforts together have led to better patient safety, outcomes and satisfaction. 

Adding value and knowledge in the field

A/Prof Shridhar has a keen interest in surgical education and served as the programme director for general surgery residency programme from 2010 to 2018. He successfully led the first ACGME-I accreditation for General Surgery residency outside of United States.
Believing strongly that doctors must learn from every patient but not learn 'on' patients, he is dedicated to making surgery safer. To this end, he is committed to raising the level of training for surgery and has initiated, developed and designed a comprehensive surgical skills training curriculum for general surgery training.

A/Prof Shridhar is the Founding Member of the Hepato-Pancreato-Biliary Association (Singapore) and serves as the current president of the HPBA(S) and president of the Society of Transplantation (SOT) Singapore. In these roles he looks forward to connecting the professionals across the country and pushing the boundaries of the discipline to serve the people better. 
Besides his work in surgical education and training, he also spends his time on his research interests. These include hepatobiliary diseases and different aspects of living donor liver transplantation, for which he has secured several competitive grants. He has published over 70 articles in peer reviewed scientific journals and over 100 presentations at international meetings. 


Journals & Publications

  1. Long-Term Oncological Safety of Minimally Invasive Hepatectomy in Patients with Hepatocellular Carcinoma: A Case-Control Study. Chang SK, Tay CW, Shen L, Iyer SG, Kow AW, Madhavan K. Ann Acad Med Singapore. 2016 Mar;45(3):91-7
  2. Outcomes of Percutaneous Cholecystostomy for Acute Cholecystitis. Pang KW, Tan CH, Loh S, Chang KY, Iyer SG, Madhavan K, Kow WC. World J Surg. 2016 Nov;40(11):2735-2744
  3. Delayed Presentation of Acute Cholecystitis: Comparative Outcomes of Same-Admission Versus Delayed Laparoscopic Cholecystectomy. Tan JK, Goh JC, Lim JW, Shridhar IG, Madhavan K, Kow AW. J Gastrointest Surg. 2017 Feb 27.
  4. Greater hypertrophy can be achieved with associating liver partition with portal vein ligation for staged hepatectomy compared to conventional staged hepatectomy, but with a higher price to pay? Chia DKA, Yeo Z, Loh SEK, Iyer SG, Bonney GK, Madhavan K, Kow AWC. Am J Surg. 2017 Aug 2
  5. ALPPS for Hepatocellular Carcinoma Is Associated with Decreased Liver Remnant Growth. Chia DKA, Yeo Z, Loh SEK, Iyer SG, Madhavan K, Kow AWC. J Gastrointest Surg. 2018 Jun;22(6):973-980
  6. Does persistent anti-HBc positivity influence the prognosis of HBsAg-negative hepatocellular carcinoma? comparative outcomes of anti-Hbc positive versus anti-Hbc negative non-B non-C HCC. Law JH, Tan JKH, Wong KYM, Ng WQ, Tan PS, Bonney GK, Iyer SG, Krishnakumar M, Kow WCA.  HPB (Oxford). 2018 Aug 4
  7. Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy. Zhao Y, Shuen TWH, Toh TB, Chan XY, Liu M, Tan SY, Fan Y, Yang H, Iyer SG, Bonney GK, Loh E, Chang KTE, Tan TC, Zhai W, Chan JKY, Chow EK, Chee CE, Lee GH, Dan YY, Chow PK, Toh HC, Lim SG, Chen Q.  Gut. 2018 Oct;67(10):1845-1854
  8. Solid Organ Transplantation in Singapore. Kee T, Shridhar Ganpathi I, Sivathasan C, Kong S, Premaraj J, Anantharaman V. Transplantation. 2018 Sep;102(9):1397-1400
  9. An international multicenter study of protocols for liver transplantation during a pandemic: A case for quadripartite equipoise Chew CA, Iyer SG, Bonney GK , et al.. J Hepatol. 2020;S0168-8278(20)30342-1. 
  10. Optimization of Outpatient Transplantation Services During the COVID-19 Pandemic: A South-East Asian Tertiary Organ Transplant Centre Experience Tan JKH, Pang NQ, Bonney GK, Kow AWC, Vathsala A, Iyer SG. Br J Surg.  2020 Aug 21

Professional Memberships

  • Founding Member, Hepato-Pancreato-Biliary Association (Singapore)
  • President, HPBA(S)
  • President, Society of Transplantation (SOT) Singapore

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