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Dr David Chen Ziyou

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  • Consultant, Department of Ophthalmology, National University Hospital
  • Consultant, Department of Ophthalmology, Alexandra Hospital
  • Adjunct Assistant Professor, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore


MBBS (S'pore), MMed (Ophth), FRCOphth, FAMS



Clinical Disciplines/Programmes:

Cataract, Glaucoma, Healthy Ageing Programme (Age Better), Refractive Surgery

Special Interests:

Medical Technology, Biodesign


Dr David Chen is a Consultant in the Department of Ophthalmology at National University Hospital (NUH) and Alexandra Hospital. He performs refractive cataract surgeries including femtosecond laser assisted cataract surgery with premium intraocular lenses (multifocal, extended depth of focus, and toric implants). In 2021, Dr Chen received training from London Vision Clinic, and performs refractive surgeries including small incision lenticule extraction (SMILE), femtoLASIK, and photorefractive keratectomy (PRK) for myopia and astigmatism correction. He also performs PRESBYOND® Laser Blended Vision for presbyopia correction. 

Dr Chen completed his undergraduate medical training at National University of Singapore (NUS), during which he was awarded the Dean’s List for his academic performance and invited to the Dean’s Dinner for his leadership qualities. He obtained his Master of Medicine (Ophthalmology) in 2019 and his specialist accreditation in 2021. During his residency training, Dr Chen was the Chief Resident from 2019 to 2020 and completed the 7th Singapore Chief Residency Programme. 

As a clinician innovator, Dr Chen's research interests include ophthalmic imaging, medical technology, and anterior segment surgeries. He has been awarded multiple research grants to develop novel medical devices and improve accessibility for community eye care. In 2022, he became the first ophthalmologist in Singapore to complete the nationally-competitive Singapore Biodesign Innovation Fellowship, a global affiliate of the renowned Stanford Biodesign program.

Dr Chen is an NUS Adjunct Assistant Professor and regularly mentors medical students from NUS Yong Loo Lin School of Medicine and NTU Lee Kong Chian School of Medicine. He has received multiple teaching awards from different organisations. 

In his free time, Dr Chen enjoys unwinding with his family and dog. He is also an avid fan of travel and photography.


  • 2023 - Young Eye Care Ambassador, Eye and Vision Health Awards, Singapore
  • 2023 - Singapore Medical Association Charity Fund Outstanding Mentor Award
  • 2022 - National Medical Research Council Research Training Fellowship Award
  • 2021 - Certificate of Appreciation (COVID-19 Community Care Facilities)
  • 2021 - Singapore Biodesign Innovation Fellowship
  • 2020 - NUHS Young Clinician Mentor Award
  • 2020 - Letter of Commendation (Tuas South Community Care Facility)
  • 2019 - European Society of Cataract and Refractive Surgeons Trainee Bursary
  • 2019 - NUHS Innovation Summit 2019 Best Poster Award (Disruptive Technologies)
  • 2019 - Young Teacher Award AY2018/2019
  • 2019, 2018, 2017 - NUS Medicine Junior Doctor Teaching Award

Journals & Publications

  1. DZ Chen, C Wong, J Lam, et al. Axial Length Elongation Profiles from 3 to 6 years olds in an Asian Paediatric Population: the Growing Up in Singapore Towards Health Outcomes Birth Cohort Study (GUSTO). Br J Ophthalmol. Article in press. [IF - 4.1]
  2. Tan DNH, Tan M, Liew H, Shen L, Ngiam KY, Chen DZ. A data-driven approach to evaluate factors affecting resident performance in cataract surgery. Int Ophthalmol. 2023; 43: 3269-3277. [IF - 1.80]
  3. Goenadi CJ, Chew KL, Gopal L, Chen DZ. Clinical outcome of bacterial endogenous endophthalmitis in 15 patients. Ann Acad Med Singap. 2023; 52: 44-47. [IF - 5.20]
  4. Jin EY, Chen DZ. Comparison of complication rates between femtosecond laser-assisted cataract surgery and conventional phacoemulsification cataract surgery. Int J Ophthalmol. 2023; 16: 156-158. [IF - 1.40]
  5. DZ Chen, JC Chong, CHN Tan. Teleophthalmology and its evolving role in a COVID-19 pandemic: A scoping review. Ann Acad Med Singap. 2021; 50: 61-76. [IF - 5.20]
  6. DZ Chen, C Chai, A Tan, et al. Microbial patterns of Acanthamoeba keratitis at a Singapore ophthalmic referral hospital: A 5-year retrospective observational study. Ann Acad Med Singap. 2021; 50: 494-496. [IF - 5.20]
  7. DZ Chen, Y Ho, Y Sasa, et al. Machine Learning-Guided Prediction of Central Anterior Chamber Depth Using Slit Lamp Images from a Portable Smartphone Device. Biosensors (Basel). 2021; 11: 182. [IF - 5.31]
  8. DZ Chen, CCA Sng, T Sangtam, et al. Phacoemulsification vs phacoemulsification with micro-bypass stent implantation in primary angle closure and primary angle closure glaucoma: A randomized single-masked clinical study. Clin Exp Ophthalmol. 2020; 48: 450-461. [IF - 5.20]
  9. DZ Chen, C Chai, W Tong, et al. Disease patterns of microbial keratitis in Singapore: A retrospective case series. Cont Lens Anterior Eye. 2019; 42: 455-461. [IF - 1.99]
  10. DZ Chen, JQH Choo, V Koh, et al. Outcomes and Complications of Ahmed Tube Implantation in Asian Eyes. J Glaucoma. 2018; 27: 733-738. [IF - 1.99]

Professional Memberships

  • Royal College of Ophthalmologists, United Kingdom
  • College of Ophthalmologists, Academy of Medicine, Singapore
  • American Academy of Ophthalmology
  • European Society of Cataract & Refractive Surgeons
  • Asia-Pacific Association of Cataract and Refractive Surgeons

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National University Health System
  • National University Hospital
  • Ng Teng Fong General Hospital
  • Alexandra Hospital
  • Jurong Community Hospital
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  • Jurong Medical Centre
  • National University Cancer Institute, Singapore
  • National University Heart Centre, Singapore
  • National University Centre for Oral Health, Singapore
  • NUHS Diagnostics
  • NUHS Pharmacy
  • Yong Loo Lin School of Medicine
  • Faculty of Dentistry
  • Saw Swee Hock School of Public Health
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