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Liver Transplant

Liver transplantation is now the accepted standard of care for patients with end-stage liver diseases, acute liver failure, and selected cases of hepatocellular carcinoma (primary liver cancer). The development of effective immunosuppressive drugs and the refinement of surgical techniques have led to remarkable improvements in the long-term success of liver transplantation.

With new surgical techniques and effective medications, the success rate of liver transplantation is quite high. About 90% of liver transplant recipients continue to do well one year after transplantation.

Transplanting only a part of the liver is possible because of the liver's unique ability to regenerate itself within a few weeks. When surgeons remove a piece of the donor's liver, the part that remains grows back quickly to its original size.

In an adult-to-child liver transplant, a smaller part of the liver (the left lobe) is typically used. In an adult-to-adult liver transplant, the larger right lobe of the liver from the living donor is used.

In Singapore, a living donor liver donation can be from relatives (e.g., spouses, siblings, parents, uncles, aunties, cousins), friends, or even a stranger (altruistic donation). In deceased donor liver donation, the organ is retrieved from deceased donors under Human Organ Transplant Act (HOTA).

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