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Dr Matthew D'Costa

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  • Consultant, Adult Kidney Transplantation Programme, National University Centre for Organ Transplantation, National University Hospital
  • Consultant, Division of Nephrology, Department of Medicine, National University Hospital


BS (Bachelor of Science; Genetics, Cell Biology, and Development), MD (Doctor of Medicine)


Renal Medicine

Clinical Disciplines/Programmes:

Adult Kidney Transplantation Programme


Born and raised in Minnesota, USA, Dr Matthew D'Costa completed his Doctor of Medicine at Ross University School of Medicine in 2011, and Internal Medicine specialty training at Marshfield Clinic in Wisconsin, USA, in 2015. Thereafter, he worked for one year as an Internal Medicine physician specialising in Hospital Medicine. He also completed the Renal Medicine training with further subspeciality training in Kidney and Pancreas Transplantation at the Mayo Clinic in Minnesota, USA in 2019. He worked as an Associate Consultant from 2019 to 2020 at Mayo Clinic in the Division of Nephrology and Hypertension.

Dr Matthew D'Costa has special clinical and research interests in nephrolithiasis, living kidney donation, kidney donors with nephrolithiasis, medical education, patient education, and quality improvement.


  • 2020 - American Transplant Congress Young Investigator Award - American Society of Transplantation
  • 2019 - Karen L. Campbell, PhD Fellow award - American Society of Nephrology
  • 2019 - CPC oral presentation - American Heart Association
  • 2019 - Distinguished Poster Award for Clinical Fellow, Young Investigators Research Symposium - Mayo Clinic Research Symposium
  • 2018 - ISN Frontiers Meeting Young Investigator Award and Travel Grant - International Society of Nephrology

Journals & Publications

  1. D'Costa MR, Haley WE, Mara KC, Enders FT, Vrtiska TJ, Pais VM, Jacobsen SJ, McCollough CH, Lieske JC, Rule AD.  Symptomatic and Radiographic Manifestations of Kidney Stone Recurrence and Their Prediction by Risk Factors: A Prospective Cohort Study. J Am Soc Nephrol. 2019 Jul; 30 (7):1251-1260
  2. D'Costa MR, Bentall A, Denic A, Schinstock CA, Merzkani MA, Park WD, Ryan MS, Alexander MP, Smith BH, Gandhi MJ, Stegall MD.  Chronic Histologic Changes Are Present Regardless of HLA Mismatches: Evidence from HLA Identical Living Donor Kidney Transplants. Transplantation. 2020 Dec 10 [Epub ahead of print]
  3. D'Costa MR, Kausz AT, Carroll KJ, Ingimarsson JP, Enders FT, Mara KC, Mehta RA, Lieske JC.  Subsequent urinary stone events are predicted by the magnitude of urinary oxalate excretion in enteric hyperoxaluria. Nephrol Dial Transplant. 2020 Dec 26 [Epub ahead of print]
  4. D'Costa MR, Pais VM, Rule AD.  Leave no stone unturned: defining recurrence in kidney stone formers. Curr Opin Nephrol Hypertens. 2019 Mar; 28 (2):148-153
  5. D'Costa MR, King RL, Alexander MP, Zhang P, Issa N, Dingli D, Amer H, Singh D, Leung N, Sukov WR, Dean PG, Habermann TM, Kukla A. EBV-negative Lymphoplasmacytic Proliferation Limited to the Renal Allograft –A Unique Presentation of a Rare Disease. 2021 May 26. KI Reports [Epub ahead of print]
  6. D'Costa MR, Taler SJ, Dominiczak AF, Touyz RM, Carey RM, Basile JN, Bursztyn M, Bhalla V, Schwartz GL.  Uncontrolled Hypertension in an Elderly Man on Multiple Antihypertensive Drugs. Hypertension. 2020 Dec; 76 (6):1658-1663 Epub 2020 Oct 26
  7. D'Costa MR, Winkler NS, Milliner DS, Norby SM, Hickson LJ, Lieske JC.  Oxalosis Associated With High-Dose Vitamin C Ingestion in a Peritoneal Dialysis Patient. Am J Kidney Dis. 2019 Sep; 74 (3):417-420 Epub 2019 Mar 22
  8. D'Costa MR, Dalvin LA, Manohar S, Maguire LJ, Grande JP, Gonsalves WI, Nasr SH, Hogan MC.  Crystalglobulin-Induced Nephropathy and Keratopathy. Kidney Med. 2019 Mar-Apr; 1 (2):71-74 Epub 2019 Feb 25
  9. D'Costa M, Savcic-Kos R, Huang J, Rule AD, Murali N.  Urological Procedures in Urolithiasis and Their Association with Chronic Kidney Disease. Clin Med Res. 2016 Jun; 14 (2):75-82 Epub 2016 June 02
  10. Merzkani MA, Mullan A, Denic A, D'Costa M, Iverson R, Kremers W, Alexander MP, Textor SC, Taler SJ, Stegall MD, Augustine J, Issa N, Rule AD. Renal function outcomes and kidney biopsy features of living kidney donors with hypertension. Clin Transplant. 2021 Mar 20:e14293.

Professional Memberships

  • American Society of Transplantation

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