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Dr Lim Shir Lynn

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  • Senior Consultant, Department of Cardiology, National University Heart Centre, Singapore
  • Assistant Professor, Yong Loo Lin School of Medicine, National University of Singapore


MBBS, MMed (Int Med), MRCP (UK)



Clinical Disciplines/Programmes:

Cardiac Critical Care, Cardiac Imaging (Echocardiography), Cardiology (Heart), General Cardiology

Special Interests:

Cardiac Arrest, Cardiorenal Syndrome

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Assistant Professor Lim Shir Lynn is a Senior Consultant with the Department of Cardiology at the National University Heart Centre, Singapore (NUHCS). She graduated from Yong Loo Lin School of Medicine, National University of Singapore (NUS) in 2006 and obtained MRCP (UK) and MMed (Int Med) in 2010. She completed her specialist training in Cardiology in 2013 and spent a year at the Alfred Hospital, Melbourne on her subspecialty fellowship in Cardiac Intensive Care. She obtained her Masters in Clinical Investigation (MCI) from NUS in 2016. 

Assistant Professor Lim's research interest lies in acute cardiovascular conditions, aligned with her sub-specialty of cardiac critical care. Her research studies focus mainly on out-of-hospital cardiac arrest, cardiogenic shock and cardiorenal syndrome. She was the founding director of the Clinical Trials Unit in NUHCS, leading the unit from 2019 to 2024. She currently leads Platform 2 of the Cardiovascular Disease National Collaborative Enterprise (CADENCE), which focuses on early-phase mechanistic clinical trials. She is a member of the Pan-Asian Resuscitation Outcomes Study (PAROS) as well as National Targeted Temperature Management (TTM) Workgroup, working to improve the care and outcomes of cardiac arrest patients in Singapore and the region. She is also an Associate Editor for Resuscitation.


  • 2016 - Academic Medicine Development Award (2016)

Journals & Publications

  1. SL Lim, CSP Lam, VFM Segers, DL Brutsaert, GW De Keulenaer. Cardiac Endothelium-Myocyte Interaction: Clinical Opportunities for New Heart Failure Therapies Regardless of Ejection Fraction. Eur Heart J. 2015;36(31):2050-2060. DOI: 10.1093/eurheartj/ehv132.
  2. SL Lim, Q Gao, Ma Shwe Zin Nyunt, L Gong, JB Lunaria, ML Lim, A Ling, CSP Lam, AM Richards, LH Ling, TP Ng. Vascular Health Indices and Cognitive Domain Function: Singapore Longitudinal Ageing Studies. J Alzheimer's Dis 2016;50(1):27-40. DOI:10.3233/JAD-150516.
  3. SL Lim, L Benson, U Dahlström, CSP Lam, LH Lund. Association Between Long-acting Nitrates and Outcomes in Heart Failure with Preserved Ejection Fraction. Circulation HF. 2017;10(4):e003534. DOI: 10.1161/CIRCHEARTFAILURE.116.003534.
  4. SL Lim, SP Chan, KY Lee, A Ching, RJ Holden, KF Miller, AB Storrow, CSP Lam, SP Collins. An East-West comparison of self-care barriers in heart failure. Eur Heart J Acute Cardiovasc Care. 2017 Dec 1:2048872617744352. DOI:10.1177/2048872617744352.
  5. J Tromp, SL Lim, WT Tay, et al. Microvascular Disease In Patients With Diabetes With Heart Failure With Reduced Versus Preserved Ejection Fraction. Diabetes Care, 2019 July. DOI: 10.2337/dc18-2515.
  6. SL Lim, CC Ong, DPS Dissanayake, SH Tay. Takotsubo and Takayasu - A Reason to Rhyme? Arthritis and Rheumatology. 2019 July. DOI: 10.1002/art.41033.
  7. SL Lim, K Smith, K Dyson, SP Chan, A Earnest, R Nair, S Bernard, BSH Leong, S Arulanandam, YY Ng, MEH Ong. Incidence and Outcomes of Out-of-Hospital Cardiac Arrest in Singapore and Victoria: A Collaborative Study. Journal of the American Heart Association. In press. DOI: 10.1161/JAHA.119.015981
  8. SL Lim, M Gandhi, KL Woo, HR Chua, YC Lim, DKL Sim, SSG Lee, YL Teoh, AM Richards, CSP Lam. Nitrates in combination with hydralazine in cardiorenal syndrome - a randomized controlled proof-of-concept study. ESC Heart Failure. In press. DOI: 10.1002/EHF2.13076
  9. SL Lim, KL Woo, E Lim, F Ng, MY Chan, M Gandhi. Impact of COVID-19 on health-related quality of in patients with cardiovascular disease: a multi-ethnic Asian study. Health Qual Life Outcomes 18, 387 (2020).
  10. KZ Kwek, R Lu, KL Woo, G Sun, KY Quek, LF Cheow, CH Chen, JY Han, SL Lim. Multiplexed single-cell leukocyte enzymatic secretion profiling from whole blood reveals patient-specific immune signature. Anal Chem. 2021;93(10):4374-4382.
  11. THK Teng, WT Tay, AM Richards, TSM Chew, I Anand, W Ouwerkerk, C Chandramouli, W Huang, CA Lawson, UT Kadam, J Yap, SL Lim, CL Hung, MR MacDonald, SY Loh, W Shimizu, J Tromp, CSP Lam. Socioeonomic status and outcomes in heart failure with reduced ejection fraction from Asia. Circ: Cardiovascular Quality and Outcomes

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