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Adj A/Prof Cindy Ho

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  • Senior Consultant, Division of Paediatric Endocrinology, Department of Paediatrics, Khoo Teck Puat - National University Children's Medical Institute, National University Hospital
  • Adjunct Associate Professor, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore


MBBS (Hons) (S'pore), MMed (Paeds) (S'pore), MRCPCH (UK)


Paediatric Medicine

Clinical Disciplines/Programmes:

Paediatric Endocrinology (Hormonal & Growth Problems)

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Adj A/Prof Cindy Ho is a paediatrician specialising in endocrinology. She looks after children with problems in growth, puberty and hormonal abnormalities such as diabetes, thyroid diseases, long term effects of cancer treatment and osteoporosis.

Adj A/Prof Ho did her undergraduate medical training in the National University of Singapore  and obtained her Bachelor of Medicine and Bachelor of surgery with Honours (MBBS, Hons) in 2004. She received many awards for academic excellence throughout her medical studies. She obtained her Master of Medicine (Paediatrics) and Membership of the Royal College of Paediatrics and Child Health (MRCPCH) in 2009 and achieved Specialist Accreditation for Paediatric Medicine in 2012.

In 2014, Adj A/Prof Ho was awarded the Ministry of Health Academic Medicine Development Award and entered the Paediatric Endocrinology Fellowship Programme of The Royal Children's Hospital, Melbourne for 1.5 years under the tutelage of Professor Margaret Zacharin. She also undertook specialist training in long-term and late effects of childhood cancer and fertility preservation techniques. She has special interests in late effects of childhood cancer survivors and bone health in children.

Adj A/Prof Ho is an Adjunct Associate Professor at the Yong Loo Lin School of Medicine, NUS and is part of the Faculty (Paediatrics) team of the NUHS Residency Programme. She is very passionate about teaching and is actively involved in the teaching, training and assessment of medical undergraduates, postgraduate paediatric doctors and nursing colleagues. She is also involved in the education sub-committee for the Asia Pacific Paediatric endocrine society (APPES) and has been invited to speak at various fellow school and conferences.

Adj A/Prof Ho is a member of the Paediatric Ethics and Advocacy Centre (PEACe) in the hospital. She also spearheads the NUH Turner Syndrome support group and contributes articles to newsletters, newspapers and magazines whenever she can.
Co-investigator in the following study/trials with grants:

  1. Whole-exome sequencing to identify genetic variants associated with severe childhood obesity, and tracking the changing prevalence of obesity related complications
  2. Metabolically unhealthy obese children have exaggerated inflammatory peripheral blood mononuclear cellular response to hyperinsulinemia
  3. Characterisation of the genomic landscape of thyroid neoplasia in the Asian population. 2015/00430
  4. Clinical and functional characterizations of genetic variants associated with dysglycaemia
  5. Development of molecular NGS-based and MLPA assays to improve the diagnostic sensitivity and accuracy of genetic tests for patients with X-linked Hypophosphatemic Rickets (XLHR)

Journals & Publications

  1. Poon, K.-S., Tan, K. M.-L., Zacharin, M., & Ho, C. W. L. (2021). A de novo mosaic phex variant causing sporadic X-linked hypophosphatemic rickets in a 2-year-old girl. Journal of Pediatric Genetics. doi: 10.1055/s-0041-1728746
  2. Tiong, Y. S., Tong, E. Y., Lee, C. C., Parameswaran, R., Cheo, T., Ho, W. L., & Yang, S. P. (2021). Prevalence of thyroid malignancy and hormonal dysfunction followingradiation exposure in childhood. Annals of the Academy of Medicine, Singapore, 50(5), 402-410. doi: 10.47102/annals-acadmedsg.2020378
  3. Ooi, D. S., Dorajoo, R., Gurung, R. L., Dehghan, R., Lim, Y. Y., Ho, C. W. L., Tay, V., Karuppiah, V., Loke, K. Y., Lim, S. C., Liu, J. J., Sng, A. A., & Lee, Y. S. (2021). Association of leukocyte telomere length with obesity-related traits in Asian children with early-onset obesity. Pediatric Obesity, 16(8). doi: 10.1111/ijpo.12771
  4. Aishworiya, R., Biswas, A., Tan, M. L., Ho, W. L., & Joseph, R. (2020). Covid-19 pandemic and children's health - mitigating unintended consequences. Annals of the Academy of Medicine, Singapore, 49(12), 1031-1033. doi: 10.47102/annals-acadmedsg.2020345
  5. Ho, C., Ng, N. B. H., & Lee, Y. S. (2020). Caring for pediatric patients with diabetes amidst the coronavirus disease 2019 storm. The Journal of Pediatrics, 223, 186-187. doi: 10.1016/j.jpeds.2020.04.067
  6. Ooi, D. S., Loke, K. Y., Ho, C. W. L., Lim, Y. Y., Tay, V., Karuppiah, V., Sng, A. A., Lai, L. Y., Lee, Y. S., & Griva, K. (2020). Self and parent-proxy rated health-related quality of life (hrqol) in youth with obesity: Are parents good surrogates? Quality of Life Research, 29(8), 2171-2181. doi: 10.1007/s11136-020-02472-y
  7. Ho, W. L., Bourne, H., Gook, D., Clarke, G., Kemertzis, M., Stern, K., Agresta, F., Heloury, Y., Clark, H., Orme, L., Jayasinghe, Y., & Zacharin, M. R. (2017). A short report on current Fertility Preservation Strategies for boys. Clinical Endocrinology, 87(3), 279-285. doi: 10.1111/cen.13377
  8. Ho, C., & Zacharin, M. (2017). Fertility Preservation in an adolescent boy: Inducing puberty and spermatogenesis prior to elective, non-urgent Bone Marrow Transplantation. Bone Marrow Transplantation, 52(5), 792-793. doi: 10.1038/bmt.2017.6
  9. Loke, K.-Y., Sng, A. A., Lim, Y. Y., Ho, C. W. L., Güemes, M., & Hussain, K. (2016). Sirolimus therapy in a child with partially diazoxide-responsive hyperinsulinaemic hypoglycaemia. Endocrinology, Diabetes & Metabolism Case Reports, 2016. doi: 10.1530/edm-16-0043
  10. Ho, W. L., & Zacharin, M. R. (2016). Thyroid carcinoma in children, adolescents and adults, both spontaneous and after childhood radiation exposure. European Journal of Pediatrics, 175(5), 677-683. doi: 10.1007/s00431-016-2692-z

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