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Dr Lim Hui Fang

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  • Senior Consultant, Division of Respiratory & Critical Care Medicine, Department of Medicine, National University Hospital
  • Assistant Professor, Clinician Educator track, NUS


MBBS (Singapore), MRCP (UK), M.Med internal medicine (Singapore)


Intensive Care Medicine, Respiratory Medicine

Clinical Disciplines/Programmes:


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Dr Lim Hui Fang is a specialist in respiratory medicine and intensive care medicine, with a special interest in severe asthma, complex airway diseases and pneumonia.

She trained as a research fellow under Dr Parameswaran Nair in McMaster University, Canada and conducted research in the role of monoclonal antibodies in severe eosinophilic asthma/ COPD, bronchial thermoplasty, lung autoimmunity and lung microbiome in severe asthma.

Her research focuses on using airway inflammometry to study innate and adaptive immune mechanistic links between severe asthma, lung infections and obesity. She is in charge of the airway inflammometry service to phenotype severe asthma patients for selection for different novel treatment such as steroid-sparing biologics, Xolair and bronchial thermoplasty.

Research interests
Airway inflammometry, role of lung macrophages
Severe Asthma, corticosteroid resistance, effects of air pollution, lung microbiome
Complex airway disease (including chronic obstructive airway disease and bronchiectasis)
Pneumonia (use of severity tools or biomarkers for early diagnosis of severe cases)

Journals & Publications

Relevant Publications in the last 5 years

  1. Lim HF, Phua J, Mukhopadhay A, Ngerng WJ, Chew MY, Sim TB, Kuan WS, Mahadevan M, Lim TK. IDSA/ATS minor criteria aided pre-ICU resuscitation in severe community-acquired pneumonia. Eur Resp J. 2013 Oct 31
  2. Phua J, Lim HF, Tay CK, Aung NW. Public awareness of sepis and stroke in Singapore: a population-based survey. Ann Acad Med Singapore. 2013 Jun; 42(6):269-77.
  3. Jason Phua, Wang Jee Ngerng, Kay Choong See, Chee Kiang Tay, Timothy Kiong, Hui Fang Lim, Mei Ying Chew, Characteristics and outcomes of culture-negative versus culture-positive severe sepsis. Critical care; 17(5):R202.
  4. Lim HF, P. Nair. The evolution of sputum cytometry to assess bronchitis Can Resp J; 20 (6): 415-6
  5. Lim HF, Nair P. Efficacy and safety of reslizumab in patients with moderate to severe eosinophilic asthma. Expert Rev Respir Med. 2015 Apr; 9(2):135-42.

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