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Dr Koo Chieh Yang Christopher

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  • Consultant, Department of Cardiology, National University Heart Centre, Singapore
  • Consultant, Division of Cardiology, Department of Medicine, Ng Teng Fong General Hospital
  • Adjunct Assistant Professor, Yong Loo Lin School of Medicine, National University of Singapore


MBBS (UK), MRCP (UK), MMed (Int Med), MCI (S’pore)



Clinical Disciplines/Programmes:

Cardiology (Heart), Cardio-Oncology, Coronary Heart Disease, General Cardiology, Hypertension, Interventional Cardiology

Special Interests:

Cardio-Oncology, Coronary Artery Disease, Sleep-Disordered Breathing, Hypertension


Dr Koo Chieh Yang Christopher is presently a Consultant at the National University Heart Centre, Singapore (NUHCS) and Adjunct Assistant Professor, Yong Loo Lin School of Medicine, National University of Singapore.

Dr Koo graduated from University College London in 2011 with a Bachelor of Medicine and Surgery (Distinction). He completed his Residency training in Internal Medicine in 2014, and was conferred both the Master of Medicine in Internal Medicine and Membership of the Royal College of Physicians (United Kingdom). Thereafter, he completed his Cardiology training in 2018 at the National University Heart Centre, Singapore and concurrently obtained his Master of Clinical Investigation.

Dr Koo’s subspecialty interests are in coronary artery disease, interventional cardiology and cardio-oncology. He performs percutaneous coronary intervention, and is a member of the 24 hour emergency primary percutaneous coronary intervention team as part of the Western STEMI network. He also sees cancer patients with concurrent heart problems in his specialised clinics.

As part of the nation's response for COVID-19, Dr Koo was appointed medical co-lead for Sungei Tengah Dormitory in 2020, the largest migrant worker dormitory in Singapore. For his contributions, he was awarded the Public Administration Medal (Bronze) in 2023.

Dr Koo’s research interests are focused on coronary artery disease. His research examines the effects of sleep-disordered breathing on cardiovascular disease. Presently, he is also investigating the effects of cancer and cancer treatment on the cardiovascular system. He serves as the current vice-president of the Singapore Chapter of the International Cardio-Oncology Society.


  • 2023 - Public Administration Medal (Bronze)
  • 2022 - Teaching Excellence Award, National University Hospital Singapore
  • 2019 - Singapore Cardiac Society Young Investigator Award (1st prize)
  • 2018 - American College of Cardiology 67th Annual Scientific Session International Fellows-in-Training Jeopardy Champion
  • 2016 - Singapore Cardiac Society Young Investigator Award (1st prize)
  • 2016 - Singapore Cardiac Society Annual Scientific Meeting Jeopardy Champion

Journals & Publications

Selected Publications:

  1. Li J, Lee ARYB, Tariq A, Lau G, Yau CE, Tan LL, Tyebally SM, Lee MX, Koo CY, et al. Comparing renal-angiotensin-aldosterone blockade regimens for long-term chemotherapy-related cardiac dysfunction: A network meta-analysis. Cardiovasc Drugs Ther. 2023; online ahead of print.
  2. Koo CY, Zheng H, Tan LL, Foo LL, Hausenloy DJ, Chng WJ, et al. Prior cancer is associated with lower atherosclerotic cardiovascular disease risk at first acute myocardial infarction. Biomedicines. 2022;10(11):2681.
  3. Koo CY, Zheng H, Tan LL, Foo LL, Seet R, Chong JH, et al. Lipid profiles and outcomes of patient with prior cancer and subsequent myocardial infarction or stroke. Sci Rep. 2021;11(1):21167.
  4. Koo CY, Tai BC, Chan DKH, Tan LL, Tan KK, Lee CH. Chemotherapy and adverse cardiovascular events in colorectal cancer patients undergoing surgical resection. World J Surg Oncol. 2021;19(1):21.
  5. Aung AT, Kristanto W, Tan MJ, Koo CY, Xu PQ, Chin CW, et al. Obstructive sleep apnea during rapid eye movement sleep in patients after percutaneous coronary intervention: a multicenter study. Sleep Breath. 2021;25(1):125-133.
  6. Koo CY, Aung AT, Chen Z, Kristanto W, Sim HW, Tam WW, et al. Sleep apnoea and cardiovascular outcomes after coronary artery bypass grafting. Heart. 2020;106(19):145-1502.
  7. Koo CY, Chua AP, Kristanto W, Koh EH, Tan ES, Abd Rahman S et al. Screening and treatment of obstructive sleep apnea in acute coronary syndrome. A randomized clinical trial. Int J Cardiol. 2020;299:20-25.
  8. Koo CY, Drager LF, Sethi R, Ho HH, Hein T, Jim MH et al. Obstructive Sleep Apnea and Diabetes Independently Add to Cardiovascular Risk After Coronary Revascularization. Diabetes Care. 2018;41(2):e12-e14.
  9. Koo CY, de la Torre AS, Loo G, Torre MS, Zhang J, Duran-Cantolla J et al. Effects of Ethnicity on the Prevalence of Obstructive Sleep Apnoea in Patients with Acute Coronary Syndrome: A Pooled Analysis of the ISAACC Trial and Sleep and Stent Study. Heart Lung Circ. 2017;26(5):486-494.
  10. Lee CH, Sethi R, Li R, Ho HH, Hein T, Jim MH, Loo G, Koo CY et al. Obstructive Sleep Apnea and Cardiovascular Events After Percutaneous Coronary Intervention. Circulation. 2016;133(21):2008-17.

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