Division of Nephrology
The Division of Nephrology at the National University Hospital, provides a continuum of care for renal patients with Stage I to Stage V Chronic Kidney Disease (CKD). Staff nephrologists work closely with renal trained nurses, dedicated medical social workers, a dietitian, renal counsellors and transplant coordinators in providing care for patients at the inpatient and outpatient settings.
The Division evaluates and manages patients with diabetic renal involvement, glomerulonephritis and other kidney diseases. As at other tertiary nephrology centres, the most dramatic renal care in the Division is for those with Stage V CKD, namely those requiring renal replacement therapy. Acute haemodialysis and continuous renal replacement therapies are provided for inpatients. The Division offers continuous peritoneal dialysis and maintenance outpatient haemodialysis at satellite and in-hospital dialysis centres, the latter for patients with severe co-morbidities.
Evaluation of patients for living and deceased donor renal transplantation and management of their pre- and post-transplant course is a core programme in the Division; staff have experience in management of high risk transplants such as crossmatch positive and ABO incompatible living donor transplants.
Training in the Division comprises core programmes in nephrology, dialysis and transplantation which are conducted weekly. Current focus in Nephrology Research includes the epidemiology of CKD and kidney failure in Singapore, the estimation and measurement of kidney function (glomerular filtration rate) in healthy and the multi-ethnic Asian CKD populations. Studies aim to improve the identification and classification of kidney health and disease using novel biomarkers.
Other collaborative research involves the development and testing of platforms for new biomarker identification in lupus, diabetes, and proteinuric kidney diseases. Research in clinical transplantation is on post transplant outcomes and complications and pharmacokinetics of immunosuppressive drugs, surrogate markers of interstitial fibrosis and tubular atrophy, whereas basic research has been initiated on immune monitoring post transplant.
The Division provides general clinical nephrology services (inpatient and outpatient). These services and programmes include:
- Chronic Haemodialysis Programme - Dialysis Centre
- Continuous Peritoneal Dialysis Programme
- Renal Nutrition Support Programme
- Renal Centre for acute dialysis support
- Renal Transplant Programme