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Prof Teh Ming

Designations:
  • Emeritus Consultant, Department of Pathology, National University Hospital
  • Emeritus Consultant, National University Cancer Institute, Singapore
Qualifications:
BA (Yale University), MD (John Hopkins), FRCPA, MRC Path (UK), FRC Path (UK)
Specialties:
Pathology
Special Interests:
GI Pathology, Renal Pathology

Biosketch

Prof Teh Ming is an Emeritus Consultant in the Department of Pathology, National University Hospital and National University Cancer Institute, Singapore. He graduated with a BA from Yale University in 1977 and a MD from Johns Hopkins University in 1981. He obtained his specialist degrees in Histopathology from the Royal College of Pathologist in Australasia and United Kingdom in 1987 and 1988 respectively.

He has published widely in peer-reviewed journals and contributed to chapters in textbooks on GI pathology/immunohistochemistry. Both his research and clinical interests are centred on the gastrointestinal tract.

Awards

  • NUHS Master Clinician Award 2019
  • National Day Awards 2022; Public Administration Bronze medal

Journals & Publications

  1. ​Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer. Cancer Discov. 2022 Mar 1;12(3):670-691. doi: 10.1158/2159-8290.CD-21-0683. PMID: 34642171 Kumar V, Ramnarayanan K, Sundar R, Padmanabhan N, Srivastava S, Koiwa M, Yasuda T, Koh V, Huang KK, Tay ST, Ho SWT, Tan ALK, Ishimoto T, Kim G, Shabbir A, Chen Q, Zhang B, Xu S, Lam KP, Lum HYJ, Teh M, Yong WP, So JBY, Tan P.
  2. ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2019161119. doi:10.1073/pnas.2019161119. PMID: 35046017; PMCID: PMC8794848. Lam TYW, Nguyen N, Peh HY, Shanmugasundaram M, Chandna R, Tee JH, Ong CB, Hossain MZ, Venugopal S, Zhang T, Xu S, Qiu T, Kong WT, Chakarov S, Srivastava S, Liao W, Kim JS, Teh M, Ginhoux F, Fred Wong WS, Ge R
  3. Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP). Gut. 2022 May;71(5):854-863. doi: 10.1136/gutjnl-2021-324057. Epub 2021 May 11. PMID: 33975867; PMCID: PMC8995828. Lee JWJ, Zhu F, Srivastava S, Tsao SK, Khor C, Ho KY, Fock KM, Lim WC, Ang TL, Chow WC, So JBY, Koh CJ, Chua SJ, Wong ASY, Rao J, Lim LG, Ling KL, Chia CK, Ooi CJ, Rajnakova A, Yap WM, Salto-Tellez M, Ho B, Soong R, Chia KS, Teo YY, Teh M, Yeoh KG.
  4. Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus. Gastroenterology. 2021 Dec;161(6):1907-1923.e26. doi:10.1053/j.gastro.2021.08.013. Epub 2021 Aug 12. PMID: 34391772. Douchi D, Yamamura A, Matsuo J, Melissa Lim YH, Nuttonmanit N, Shimura M, Suda K, Chen S, Pang S, Kohu K, Abe T, Shioi G, Kim G, Shabbir A, Srivastava S, Unno M, Bok-Yan So J, Teh M, Yeoh KG, Huey Chuang LS, Ito Y
  5. Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation. Genome Biol. 2021 Jun 1;22(1):167. doi:10.1186/s13059-021-02375-2. Erratum in: Genome Biol. 2021 Jun 17;22(1):181. PMID: 34074348; PMCID: PMC8170989. Padmanabhan N, Kyon HK, Boot A, Lim K, Srivastava S, Chen S, Wu Z, Lee HO, Mukundan VT, Chan C, Chan YK, Xuewen O, Pitt JJ, Isa ZFA, Xing M, Lee MH, Tan ALK, Ting SHW, Luftig MA, Kappei D, Kruger WD, Bian J, Ho YS, Teh M, Rozen SG, Tan P.
  6. Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair. Gut. 2021 Oct;70(10):1833-1846. doi:10.1136/gutjnl-2020-322779. Epub 2020 Dec 8. PMID: 33293280; PMCID: PMC8458072. Matsuo J, Douchi D, Myint K, Mon NN, Yamamura A, Kohu K, Heng DL, Chen S, Mawan NA, Nuttonmanit N, Li Y, Srivastava S, Ho SWT, Lee NYS, Lee HK, Adachi M, Tamura A, Chen J, Yang H, Teh M, So JB, Yong WP, Tan P, Yeoh KG, Chuang LSH, Tsukita S, Ito Y
  7. WBP2 promotes gastric cancer cell migration via novel targeting of LATS2 kinase in the Hippo tumor suppressor pathway. FASEB J. 2021 Feb;35(2):e21290. doi: 10.1096/fj.202000393R.PMID: 33475198. Hum M, Tan HJ, Yang Y, Srivastava S, Teh M, Lim YP.
  8. AQP5 enriches for stem cells and cancer origins in the distal stomach. Nature.2020 Feb;578(7795):437-443. doi: 10.1038/s41586-020-1973-x. Epub 2020 Feb 5. PMID: 32025032. Tan SH, Swathi Y, Tan S, Goh J, Seishima R, Murakami K, Oshima M, Tsuji T, Phuah P, Tan LT, Wong E, Fatehullah A, Sheng T, Ho SWT, Grabsch HI, Srivastava S, Teh M, Denil SLIJ, Mustafah S, Tan P, Shabbir A, So J, Yeoh KG, Barker N.
  9. DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia. Gut. 2020 Oct;69(10):1738-1749. doi: 10.1136/gutjnl-2019-319002.Epub 2020 Jan 14. PMID: 31937549; PMCID: PMC7497583. Krishnan V, Lim DXE, Hoang PM, Srivastava S, Matsuo J, Huang KK, Zhu F, Ho KY, So JBY, Khor C, Tsao S, Teh M, Fock KM, Ang TL, Jeyasekharan AD, Tan P, Yeoh KG, Ito Y
  10. An LCM-based genomic analysis of SPEM, Gastric Cancer and Pyloric Gland Adenoma in an Asian cohort. Mod Pathol. 2020 Oct;33(10):2075-2086. doi: 10.1038/s41379-020-0520-5. Epub 2020 Apr 8. PMID: 32269290. Srivastava S, Huang KK, Rebbani K, Das K, Fazreen Z, Yeoh KG, Tan P, Teh M.


 

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