Dr Mahesh Babu Ramamurthy trained in paediatrics in India and attained the gold medal in the FCPS exams in 1993. Subsequently, Dr Mahesh underwent subspecialty training in paediatric intensive care in the UK, and paediatric pulmonology in the US. He was practicing as a Consultant Paediatric Pulmonologist in Bangalore, India for 10 years, where he set up a tertiary referral center for paediatric respiratory diseases.

He joined the National University Hospital, Singapore in October 2009. Dr Mahesh specialises in paediatric pulmonology and sleep, and his clinical interests include childhood respiratory conditions, including asthma and allergies, flexible paediatric bronchoscopy and sleep studies.

He has been a co-ordinator and member of consensus committee in framing the National Guidelines for Bronchial Asthma in Children, the National Guidelines for Rational Therapy of Respiratory tract infection in children and the National Guidelines for diagnosis and management of Pulmonary Tuberculosis in children, in India. He has delivered 2 Oration lectures and at least 300 lectures as Guest speaker and invited faculty in various National conferences and Forums in India. Dr Mahesh was also involved in the setting up of the first Paediatric Sleep Lab in India.