Professor Roger Ho completed his medical degree (MBBS) and higher research degree (MD) at University of Hong Kong and did his basic and advanced Psychiatry training at National University of Singapore. He is a fellow of the Royal College of Psychiatrists (UK), Royal College of Physicians (Canada), Academy of Medicine (Singapore) and Royal College of Physicians (Edinburgh).

He currently works as a Professor and Senior Consultant Psychiatrist at the Department of Psychological Medicine, NUS and NUH. His clinical expertise covers all aspects of adult psychiatry, such as adult ADHD, depressive disorder, bipolar disorder, anxiety disorders, schizophrenia, and personality disorders. He conducts research and specializes in Adult ADHD assessment based on clinical interview, questionnaires and assessment of the frontal lobe function using the functional near infra-red spectroscopy (fNIRS). He also provides services to the elderly who prefer to speak Cantonese. 

Prof Ho is involved in multiple research endeavours, which primarily aim to study the interface between psychiatry and medicine. His earlier research involved elucidating psychiatric symptoms associated with systemic lupus erythematosus. He also serves as a Clinical Lead in the Functional Near Infrared Spectroscopy (fNIRS) Group, Institute of Health and Technology (iHeathtech) at National University of Singapore. His recent research extended to study the effects of antidepressants on the immune system in animal, as well as the application of technology in clinical services and research, including functional near infrared spectroscopy (fNIRS) assessing depression, borderline personality disorder, bipolar disorder and adult ADHD. He also continues to be involved in publications related to his earlier research interests. He is one of the pioneer researchers who published papers related to mental health during the early stage of COVID-19 pandemic. He is the author or co-author of more than 500 articles published in peer-reviewed journals. He is an Associate Editor and editorial board member for various prestigious international journals including Comprehensive Psychiatry, Scientific Reports and BJPsych Advances. In 2021, he was identified by the Web of Science as one of the most highly cited researchers in the world.

Prof Ho is extensively involved in medical education. He disseminated psychiatric knowledge through publications of academic books with global influence. The most recent example is the co-authorship and publication of a postgraduate textbook, Revision Notes in Psychiatry (3rd edition), CRC Press 2013 and this book has been one of the most commonly used reference texts since 1998 by psychiatric trainees in Commonwealth countries.