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Dr David Chen Ziyou

  • Associate Consultant, Department of Ophthalmology, National University Hospital
  • Associate Consultant, Department of Ophthalmology, Alexandra Hospital
MBBS (S'pore), MMed (Ophth), FRCOphth, FAMS
Ophthalmology (Eye)
Cataract, Glaucoma, Healthy Ageing Programme (Age Better), Refractive Surgery
Special Interests:
​Medical Technology, Biodesign


Dr David Chen is an Associate Consultant in the Department of Ophthalmology at National University Hospital (NUH) and Alexandra Hospital. He is currently pursuing sub-specialty training in the field of complex cataract and refractive surgery. He performs small incision lenticule extraction (SMILE), femtoLASIK, photorefractive keratectomy (PRK) for myopia correction. He also performs PRESBYOND® Laser Blended Vision for presbyopia correction. 

Dr Chen completed his undergraduate medical training at the Yong Loo Lin School of Medicine, National University of Singapore (NUS) in 2015. He was awarded the Dean’s List for his academic performance and invited to the Dean’s Dinner for his leadership qualities. He obtained his Master of Medicine (Ophthalmology) in 2019 and his specialist accreditation in 2021. During his residency training, Dr Chen served as the Chief Resident from 2019 to 2020, and joined the 7th Singapore Chief Residency Programme. 

Dr Chen's research interests include ophthalmic imaging, medical technology, and anterior segment surgeries (including cataract and glaucoma surgeries). He has been awarded the Junior Pitch For Fund grant in 2017, the NUH Clinician Scientist Program – Residency (NCSP-R) grant in 2018, National University Health System (NUHS) Innovation Grant in 2019, NUHS Seed Fund in 2020, and NUHS Summit Programme in Innovation in 2022. He aspires to be a clinician-innovator and has completed the Innovation Fellowship with the Singapore Biodesign programme, a competitive national level fellowship to further hone his knowledge in MedTech and healthcare innovation.

Dr Chen also conducts regular clinical teachings for medical students. He is a Clinical Lecturer at the NUS Yong Loo Lin School of Medicine and a Clinical Teacher at Lee Kong Chian School of Medicine. He has also been a House Mentor for NUS Medicine since 2015, providing guidance to first year medical students and supporting their transition into college.


  • 2021 - Singapore Biodesign Innovation Fellowship
  • 2020 - NUHS Young Clinician Mentor Award
  • 2020 - Letter of Commendation (Tuas South Community Care Facility) 
  • 2019 - European Society of Cataract and Refractive Surgeons Trainee Bursary
  • 2019 - NUHS Innovation Summit 2019 Best Poster Award (Disruptive Technologies)
  • 2019 - Young Teacher Award AY2018/2019
  • 2019, 2018, 2017 - NUS Medicine Junior Doctor Teaching Award

Journals & Publications

​Selected Publications:
1. DZ Chen, CCA Sng. Safety and Efficacy of Microinvasive Glaucoma Surgery. J Ophthalmol. 2017; 2017: 3182935. [IF = 1.45]
2. DZ Chen, V Koh, M Tan, et al. Peripheral retinal changes in highly myopic young Asian eyes. Acta Ophthalmol. 2018; 96: e846-e851. [IF - 3.36]
3. DZ Chen, JQH Choo, V Koh, et al. Outcomes and Complications of Ahmed Tube Implantation in Asian Eyes. J Glaucoma. 2018; 27: 733-738. [IF - 1.99]
4. D Chen, C Chai, W Tong, et al. Disease patterns of microbial keratitis in Singapore: A retrospective case series. Cont Lens Anterior Eye. 2019; 42: 455-461. [IF - 1.99]
5. DZ Chen, CCA Sng, T Sangtam, et al. Phacoemulsification vs phacoemulsification with micro-bypass stent implantation in primary angle closure and primary angle closure glaucoma: A randomized single-masked clinical study. Clin Exp Ophthalmol. 2020; 48: 450-461. [IF - 4.21]
6. D Chen, Y Ho, Y Sasa, et al. Machine Learning-Guided Prediction of Central Anterior Chamber Depth Using Slit Lamp Images from a Portable Smartphone Device. Biosensors (Basel). 2021; 11: 182. [IF - 5.31]
7. DZ Chen, C Chai, A Tan, et al. Microbial patterns of Acanthamoeba keratitis at a Singapore ophthalmic referral hospital: A 5-year retrospective observational study. Ann Acad Med Singap. 2021; 50: 494-496. [IF - 2.47]
8. DZ Chen,  JC Chong, CHN Tan. Teleophthalmology and its evolving role in a COVID-19 pandemic: A scoping review. Ann Acad Med Singap. 2021; 50: 61-76. [IF - 2.47]

Book Chapters:
Essentials of Ophthalmology: For Medical School and Beyond, Glaucoma

Professional Memberships

  •  Royal College of Ophthalmologists, United Kingdom
  • College of Ophthalmologists, Academy of Medicine, Singapore
  • American Academy of Ophthalmology
  • European Society of Cataract & Refractive Surgeons
  • Asia-Pacific Association of Cataract and Refractive Surgeons


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