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Dr Daryl Chia Kai Ann

  • Associate Consultant, Division of General Surgery (Upper Gastrointestinal Surgery), Department of Surgery, National University Hospital
  • Associate Consultant, Division of General Surgery (Upper Gastrointestinal Surgery), Department of Surgery, Alexandra Hospital
MBBS (Singapore), MRCS (Ire), MCI (NUS), MMed (Surgery), FRCS (Edin)
Surgery, Surgical Oncology
Bariatric & Metabolic Surgery, Hernia Surgery, Minimally Invasive Surgery, Surgical Oncology (Upper Gastrointestinal Surgery), Upper Gastrointestinal Surgery
Special Interests:
​Upper Gastrointestinal Surgery (Esophageal and Gastric Cancer), Metabolic and Bariatric Surgery, Benign Foregut Disorders, Diagnostic & Therapeutic Endoscopy, Minimally-Invasive Surgery 


Dr Daryl Chia graduated from the National University of Singapore (NUS) in 2013 and joined the General Surgery Residency Programme at the National University Hospital in 2016. He obtained Master of Clinical Investigation (NUS) in 2019 while in training, completed General Surgery training and obtained the Fellowship of the Royal College of Surgeons of Edinburgh in 2021. He is accredited as a Specialist in General Surgery by the Specialist Accreditation Board. 

Dr Chia has a sub-speciality interest in Upper Gastrointestinal Surgery and has joined the Department of Surgery in NUH & Alexandra Hospital as an Associate Consultant. His clinical interests include bariatric surgery, benign foregut conditions (reflux disease, achalasia, paraesophageal hernia), esophageal and gastric cancers, advanced endoscopy, enteral access procedures and laparoscopic hernia repair. 

In addition to his clinical work, Dr Chia is involved in both clinical and translational research. He was awarded the ExxonMobil-NUS Research Fellowship and NUHS Seed Grant to pursue further research in gastric cancer. He has authored more than 20 papers and multiple poster and oral presentations at international meetings. He is also involved in both Undergraduate & Postgraduate Medical Education and was past recipient of the NUS Medicine Junior Doctor Teaching Award (2019) and NUHS Residents’ Choice Award (2020,2022). He currently serves as Clinical Tutor, Yong Loo Lin School of Medicine and Core Faculty, Post-Graduate Year 1 (PGY1) programme.


2022 - ExxonMobil-NUS Research Fellowship 
2020 - NUS Medicine Junior Doctor Teaching Award
2020 - Residents’ Choice Award

Journals & Publications

  1. Chia DKA, Sundar R, Guowei K, ..., So J, Yong WP. Outcomes of a Phase II Study of Intraperitoneal Paclitaxel plus Systemic Capecitabine and Oxaliplatin (XELOX) for Gastric Cancer with Peritoneal Metastases. Ann Surg Oncol 2022. In press
  2. Chia DKA, Gwee YX, Sundar R. Resistance to systemic immune checkpoint inhibition in the peritoneal niche. J Immunother Cancer. 2022 Jun;10(6):e004749. doi: 10.1136/jitc-2022-004749. PMID: 35728873.
  3. Gwee YX, Chia DKA, So J, Ceelen W, Yong WP, Tan P, Ong CJ, Sundar R. Integration of Genomic Biology Into Therapeutic Strategies of Gastric Cancer Peritoneal Metastasis. J Clin Oncol. 2022 Jun 1:JCO2102745. doi: 10.1200/JCO.21.02745. Epub ahead of print. PMID: 35649219.
  4. Chia DKA, Lim Z, Ang JJ, Tambyah PA, Lau KSH, Ong J, Chow VTK, Allen DM, Fung J, Lau KJX, Luhung I, Schuster SC, Lee CN, Kim G, So JBY, Lomanto D, Shabbir A. Coronavirus viability in surgical plume and methods for safe disposal: a preclinical model. Br J Surg. 2021 Dec 17;109(1):15-20. doi: 10.1093/bjs/znab385. PMID: 34792098.
  5. Ang JJ, Chia DKA, Chan DKH. Lymphocyte-White Cell Ratio Is a Novel Marker of Morbidity Following Colorectal Cancer Surgery. J Surg Res. 2021 Mar;259:71-78. doi: 10.1016/j.jss.2020.11.027. Epub 2020 Dec 3. PMID: 33279846.
  6. Chan DKH, Ang JJ, Tan JKH, Chia DKA. Age is an independent risk factor for increased morbidity in elective colorectal cancer surgery despite an ERAS protocol. Langenbecks Arch Surg. 2020 Aug;405(5):673-689. doi: 10.1007/s00423-020-01930-y. Epub 2020 Jul 8. PMID: 32642863.
  7. Chia DKA, So JBY. Recent Advances in Intra-peritoneal Chemotherapy for Gastric Cancer. J Gastric Cancer. 2020 Jun;20(2):115-126. doi: 10.5230/jgc.2020.20.e15. Epub 2020 Apr 10. PMID: 32595996; PMCID: PMC7311211.
  8. Chia DKA, Lomanto D, Wijerathne S. Patient-Reported Outcomes and Long-Term Results of a Randomized Controlled Trial Comparing Single-Port Versus Conventional Laparoscopic Inguinal Hernia Repair. World J Surg. 2020 Jul;44(7):2191-2198. doi: 10.1007/s00268-020-05443-z. PMID: 32123978.
  9. Chia DKA, Kim G, Chang HSY, Toh BC, So JBY, Shabbir A. Kamikawa Double-Flap Reconstruction After Minimally Invasive Ivor-Lewis Esophagectomy. Ann Thorac Surg. 2019 Jul;108(1):e57-e59. doi: 10.1016/j.athoracsur.2019.01.077. Epub 2019 Mar 12. PMID: 30872101.

Professional Memberships

  • Member, Royal College of Surgeons (Ire)
  • Fellow, Royal College of Surgeons (Edin) 


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