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Dr Chan Hwei Wuen

  • Consultant, Department of Ophthalmology, National University Hospital
  • Consultant, Healthy Ageing Programme (Age Better), Alexandra Hospital
  • Assistant Professor, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore
MBBS (UCL), MMed (Ophth), FAMS, FRCOphth (UK)
Ophthalmology (Eye)
Cataract, General Ophthalmology, Healthy Ageing Programme (Age Better), Retina (Medical), Retina (Surgical)


Dr Chan Hwei Wuen is a Consultant Ophthalmic Surgeon at the Department of Ophthalmology, National University Hospital and Alexandra Hospital.

Dr Chan received formal medical training at the University College London (UCL) and her first exposure to Ophthalmology was during her time at Moorfields Eye Hospital as an undergraduate, which fuelled her interest to pursue a career in this specialty. She completed her residency training in Ophthalmology at the National University Hospital, Singapore, in June 2016. During her residency training, Dr Chan served as the Chief Resident from 2014-2015. She is actively involved in undergraduate and postgraduate teaching and was awarded the NUS MedSoc Outstanding Tutor Award. Dr Chan holds a joint appointment on the NUS Clinical Faculty Scheme. She is a member of the Royal College of Ophthalmologists (UK).

Upon completion of local fellowship training in Visual Electrophysiology, Medical Retina and Vitreoretinal Surgery, Dr Chan received the MOH Health Manpower Development Plan (HMDP) fellowship award and pursued further subspecialty training overseas. During her time at Moorfields Eye Hospital from 2019 to 2020, she was trained in Ophthalmic Genetics under Prof Andrew Webster, Prof Michel Michaelides, Prof Mariya Moosajee and Prof Omar Mahroo. This was followed by further fellowship training at the Ghent University Hospital, Belgium under the tutelage of Prof Bart Leroy in Ophthalmic Genetics where she was involved in several gene therapy trials including Luxturna for the treatment of biallelic mutation in RPE65 mutation-related inherited retinal dystrophy and Sepofarsen for CEP290-associated Leber Congenital Amaurosis . Aside from her subspecialty interests, Dr Chan is also proficient in the management of adult cataracts and is trained in femtosecond laser assisted cataract surgery.


  • 2020 - Value Driven Outcome (VDO) Excellence Award (NUH)
    Recognises clinicians who have contributed towards elevating healthcare outcome and reducing costs for their patients.
  • 2019 - Women of the Future Award: Professions (South East Asia)
  • 2019 - Healthcare Manpower Development Program (HMDP) Award, Ministry of Health, Singapore (SGD 484,766.00)
  • 2017 - NUS Special Recognition Award for Undergraduate Medical Teaching 
  • 2016 - Department of Ophthalmology, Best Tutor Award for NUS Undergraduate Medical Teaching
  • 2016 - NUS MedSoc Outstanding Tutor Award

Journals & Publications

  1. DK Lim*, HW Chan*, C Zheng, MC Aquino, WL Wong, R Ritch, PTK Chew, et al. Quantitative assessment of changes in anterior segment morphology after argon laser peripheral iridoplasty: findings from the EARL Study Group. Clin Exp Ophthalmol. 2019 Jan;47(1):33-40. PMID: 30098125 (*co-first authors).
  2. HW Chan, B Yang, W Wong, P Blakeley, I Seah, QSW Tan, H Wang, M Bhargava, HA Lin, CH Chai, EA Mangunkusumo, N Thet, YS Yuen, R Sethi, S Wang, W Hunziker, G Lingam, X Su, et al. A Pilot Study on MicroRNA Profile in Tear Fluid to Predict Response to Anti-VEGF Treatments for Diabetic Macular Edema. J Clin Med. 2020 Sep 10;9(9):2920. doi: 10.3390/jcm9092920. PMID: 32927780; PMCID: PMC7564365.
  3. A Tanner*, HW Chan*, JS Pulido, G Arno, R Ba-Abbad, N Jurkute, AG Robson, CA Egan, H Knight, A Calcagni, RL Taylor, E Lenassi, GC Black, AT Moore, M Michaelides, AR Webster, OA Mahroo, et al. Clinical and genetic findings in CTNNA1-associated macular pattern dystrophy, Ophthalmology (2020), doi: (*co-first author). PMID: 33137351.
  4. ER Schiff, VK Tailor, HW Chan, M Theodorou, AR Webster, M Moosajee, et al. Novel Biallelic Variants and Phenotypic Features in Patients with SLC38A8-Related Foveal Hypoplasia. Int J Mol Sci. 2021 Jan 24;22(3):1130. doi: 10.3390/ijms22031130. PMID: 33498813.
  5. HW Chan, VK Tailor, S Malka, E Schiff, MM Neveu, M Theodorou, M Moosajee, et al. Prospective study of the phenotypic and mutational spectrum of ocular albinism and oculocutaneous albinism. Genes (Basel). 2021 Mar 30;12(4):508. doi: 10.3390/genes12040508. PMID: 33808351.

Professional Memberships

  • Fellow, Academy of Medicine, Singapore (since Aug 2016)
  • Fellow, Royal College of Ophthalmologists, United Kingdom (since December 2016)                         
  • Member, Singapore Society of Ophthalmology (since 2011)
  • Member, European Society of Cataract and Refractive Surgeons (since 2012
  • Member, European Society of Retinal Specialists (since May 2017)
  • Member, Association for Research in Vision and Ophthalmology (ARVO) (since 2017)
  • Member, International Society for Genetic Eye Diseases and Retinoblastoma (ISGEDR) (since 2019)


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