Stroke is an important cerebrovascular disease that is rising both in incidence and prevalence globally.
The focus of our research is to optimise the use of acute reperfusion therapies by complementing radiologic and sonographic methods to achieve recanalisation of the occluded artery and improve clinical outcomes.
As intracranial stenosis is prevalent in our community, we have undertaken several initiatives to examine the contribution of intracranial stenosis with respect to cerebrovascular reserves, electrographic changes and stroke recurrence.
Through the use of telemedicine, we have also embarked on several initiatives to determine the incidence of paroxysmal atrial fibrillation and blood pressure control in stroke patients. We have also engaged academic and industry partners to assess the use of transcranial magnetic stimulation, brain-computer interface and botulinum injections to facilitate rehabilitation in our patients.
Our objectives in the laboratory are to better understand the reasons why strokes occur, why some patients are resistant to "standard treatment" and why complications such as cerebral haemorrhage occur. Through our collaborations with engineers and scientists in academia and industry, we are working to identify high-risk patients by developing biomarker-based and novel treatment strategies.