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19
Sep
2022

Mum with colorectal cancer gets new lease of life with son's liver

Channel NewsAsia

​A team from National University Health System has successfully conducted a liver transplantation on a Stage 4 colorectal cancer patient whose cancer has spread to the liver. Madam Lim Gek Meng was initially diagnosed at Ng Teng Fong General Hospital in October 2020 and was immediately put on chemotherapy. In July 2022, Mdm Lim successfully underwent liver transplant at National University Centre for Organ Transplantation, in a multicentre initiative involving more than 50 professionals across National University Health System, including National University Hospital and National University Cancer Institute Singapore. This was Singapore's first such transplant and according to current literature, the first in the region. 

The team led by A/Prof Glenn Bonney, Consultant in National University Hospital's Division of Hepatobiliary and Pancreatic Surgery, Adult Liver Transplantation Programme at National University Centre for Organ Transplantation and Division of Surgical Oncology, National University Cancer Institute Singapore, as well as international experts, formulated a set of consensus guideline with 44 criteria to select and manage patients who are candidates for the liver transplant.

Channel NewsAsia cited A/Prof Bonney as saying that he felt privileged to be able to work in a system that can generate such care, where a Stage 4 colorectal cancer patient is able to be cancer-free following the transplant.


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18
Sep
2022

Mum with colorectal cancer gets new lease of life with son's liver

The Straits Times © SPH Media Limited. Reproduced with permission

​A team from National University Health System has successfully conducted a liver transplantation on a Stage 4 colorectal cancer patient whose cancer has spread to the liver. Madam Lim Gek Meng was initially diagnosed at Ng Teng Fong General Hospital in October 2020 and was immediately put on chemotherapy. In July 2022, Mdm Lim successfully underwent liver transplant at National University Centre for Organ Transplantation, in a multicentre initiative involving more than 50 professionals across National University Health System, including National University Hospital and National University Cancer Institute Singapore. This was Singapore's first such transplant and according to current literature, the first in the region. 

The team led by A/Prof Glenn Bonney, Consultant in National University Hospital's Division of Hepatobiliary and Pancreatic Surgery, Adult Liver Transplantation Programme at National University Centre for Organ Transplantation and Division of Surgical Oncology, National University Cancer Institute Singapore, as well as international experts, formulated a set of consensus guideline with 44 criteria to select and manage patients who are candidates for the liver transplant.

Prof Chng Wee Joo, Director of National University Cancer Institute Singapore, said that the success of the transplant highlighted a new treatment paradigm, where specific patients with Stage 4 colorectal cancer who fulfilled the necessary criteria may be candidates for liver transplantation.

The Straits Times and various media quoted Mdm Lim as saying that she is "terribly grateful to all the doctors, nurses and even admin staff" who have helped her in the last two years".  

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16
Sep
2022

同时移植胰脏肾脏 能治愈糖尿病?(Can transplanting pancreas and kidney simultaneously cure diabetes?)

U-weekly. Reproduced with permission.

​A/Prof Tiong Ho Yee, Senior Consultant, Adult Kidney & Pancreas Transplantation Programme, NUCOT and Director of the National Pancreas Transplant Programme, said that simultaneous kidney and pancreas transplant may increase the quality of life and survival rate of patients with type 1 or type 2 diabetes compared to other available treatment.

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13
Sep
2022

How her child’s battle against cancer inspired this mum to help others

Others

​Ms Lesli Berggren, founder and executive director of charity organisation LOVE, NILS, shared how her son Nils had received treatment and a stem cell transplant for stage 4 lymphoma at NUH under “the amazing care of the children’s cancer department”. In 2015, Ms Berggren began hosting annual toy donation events for the children’s cancer wards at NUH to memorialise Nils’ death, which led her to register LOVE, NILS as a charity in 2017. The charity donated $100,000 in its first year to fund a Care Coordinator position in NUH’s paediatric oncology wards.

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22
Aug
2022

Kidney swop transplant gives woman new lease of life

The Straits Times © SPH Media Limited. Reproduced with permission

​Asst Prof Hersharan Kaur Sran, Senior Consultant and Medical Director of the Adult Kidney Transplantation Programme, NUCOT, provided comments on paired kidney exchange transplant. She explained that there would be a higher risk of an acute rejection of the organ, higher risks of infections and a longer hospital stay for patients who are medically incompatible for a transplant.

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11
Aug
2022

Marketing Event Awards 2022: Shortlist announced

Others

​NUCOT’s "The Transplant Colloquium 2022" was shortlisted as one of the finalists for the “Best Event for a Targeted Community” and “Best Use of Hosting Platforms” categories at the Marketing Events Awards 2022.

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3
Aug
2022

Man needs urgent liver transplant, wife struggles to cope

The New Paper © SPH Media Limited. Reproduced with permission

​Several media reported that Mr Xiong, a patient warded at NUH, urgently needs liver transplant after his liver had ruptured abruptly resulting in liver failure. The reports mentioned that 13 people who stepped up as potential donors were deemed unsuitable because of underlying health conditions. His wife, Ms Yu, had first received the distressing call on 28 July from the hospital and was told that her husband was experiencing acute liver failure and had lost consciousness. Mr Xiong remains in the intensive care unit. He has been reliant on an artificial liver machine, though doctors are uncertain of how long he can survive even with the machine temporarily performing the failing organ’s functions. Mr Xiong’s doctors, close family and friends have been searching for his potential donors.

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29
Jun
2022

Health Suites: Greater assurance to be a living donor in Singapore

Others

​A/Prof Shridhar Iyer, Surgical Director & Senior Consultant, Adult Liver Transplantation Programme, NUCOT, shared his views on liver donor transplants. A/Prof Iyer said that deceased donor liver donation is unable to keep up with the growing demand for liver donors, which makes living donor liver transplantation an important alternative, especially in Singapore.

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26
Jun
2022

Social media appeals lead to more liver transplants from strangers

The Sunday Times © SPH Media Limited. Reproduced with permission

​A study conducted by a team of clinicians from NUCOT found that there were no cases of liver donor deaths among 204 procedures performed by NUCOT and there were less than 10 per cent of donors experiencing complications which were largely minor. A/Prof Shridhar Iyer, Surgical Director & Senior Consultant, Adult Liver Transplantation Programme, NUCOT also noted that online appeals have resulted in more people coming forward to donate their livers to strangers in recent years. A/Prof Shridhar hopes that the study will assure the public it is safe to be a living liver donor in Singapore. 


The Sunday Times also noted that since 1990, there has been more than 500 liver transplants from both living and deceased donors in Singapore, with most of these procedures performed by NUCOT.

The Sunday Times also featured NUCOT's altruistic donor Mr Sakthibalan Balathandautham who encouraged people who wish to donate their livers or other organs, such as kidneys or pancreas, to consult their doctors to check on their suitability. He added that potential donors should do so only when they feel confident about it and are able to spare the time for the procedure and recovery. He noted that donations require a lot of commitment and the donor has to be healthy.



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26
Jun
2022

Kidney transplants in S’pore fall over past 2 years amid pandemic

The Sunday Times © SPH Media Limited. Reproduced with permission

​The Sunday Times interviewed Dr Hersharan Kaur Sran, Senior Consultant, Adult Kidney & Pancreas Transplantation Programme, NUCOT, who commented that NUH’s transplant team received fewer referrals from kidney doctors, who were swamped during COVID-19, and transplants involving deceased donors dropped significantly due to concerns about infection transmission, among other things. Dr Sran who is also the Medical Director for NUCOT’s Adult Kidney Transplantation Programme explained that organs from higher-risk donors – such as people who were older or less healthy – were turned down. This was because such transplants require more medical resources and increase the risk of recipients having to stay longer in hospitals or needing intensive care. 


ST also interviewed a NUCOT patient, Mr Koh Cheun Yang, who has been on the kidney transplant wait list for 14 years. He has had both kidneys removed due to a condition which results in cyst forming in them, and goes for dialysis three times a week. While his doctors at NUH told him that the pandemic would impact his chances of getting a new kidney, he remained upbeat.


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26
Jun
2022

等肾移植者增 可等长达 8 年 (The number of patients waiting for kidney transplant has increased; wait can be up to 8 years)

新明日报 © SPH Media Limited. Reproduced with permission

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22
Jun
2022

Storage bank for human poop to treat diseases launched

The Straits Times © SPH Media Limited. Reproduced with permission

​The first gut microbiome banking service in Southeast Asia, launched by health startup Amili and healthtech firm Cordlife, allows people to preserve the healthy microbes in their digestive tract, so that they may be used in the future to treat diseases such as severe diarrhoea and inflammatory bowel disease. Faecal transplants have been approved in Singapore for treating patients infected with the Clostridium difficile (C.diff) bacteria in the large intestine or colon. In 2014, Amili’s co-founder, A/Prof David Ong, performed the first poop transplant at NUH to treat a patient infected with the C.diff bacterium. Amili is currently conducting clinical trials in NUH for microbiome transplants on patients with inflammatory bowel disease, a condition where one's colon and rectum become inflamed. 

Media ArticlesNUH in the News
21
Jun
2022

Health Matters – Liver donor transplants

Channel NewsAsia

​A/Prof Shridhar Iyer, Surgical Director & Senior Consultant, Adult Liver Transplantation Programme, NUCOT, shared his views on liver donor transplants. He said that the recipient benefits must be weighed against the risks, and there was an ethical dilemma of balancing the risks between the donor and the recipient. 

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20
Jun
2022

本地活体捐肝者死亡率为零 仅1.5%出现严重病发症 (Zero mortality rate among living liver donors in Singapore; only 1.5% suffer serious complications)

联合早报 © SPH Media Limited. Reproduced with permission

​A study conducted by a team of clinicians from NUCOT shows zero donor mortality and low risks of complications in liver donor surgeries performed at NUCOT. The study also shows that despite the inherent challenges faced by Singapore, outcomes of living donor hepatectomy in NUCOT can either match or are even better than the favourable outcomes reported in other centres worldwide. News reports also highlighted that NUH performed Singapore’s first deceased donor liver transplantation in 1990 and the first living donor liver transplantation in 1996. Since then, more than 500 living and deceased donor liver transplants have been performed locally, with NUCOT accounting for 453 cases, of which 227 were living donor liver transplants.   


Lianhe Zaobao quoted A/Prof Shridhar Iyer, Surgical Director & Senior Consultant, Adult Liver Transplantation Programme, NUCOT, who commented that deceased donor liver donation is unable to keep up with the growing demand for liver donors, which makes living donor liver transplantation an important alternative, especially in Singapore. 

Channel 8 also quoted A/Prof Shridhar, who hopes that people can talk about organ donation when they are healthy and active, so that there will be more organs to help those in need. 



Media ArticlesNUH in the News
7
May
2022

‘Poop lab’ studies gut health to help treat illnesses

Others

​A/Prof Jeremy Lim, Director of the Leadership Institute for Global Health Transformation, NUS Saw Swee Hock School of Public Health, who is also the co-founder of start-up Amili said that Amili was started so that the region would have its own research and capability to do poop transplants. Amili is partnering with National University Hospital to run clinical studies on using these transplants to treat children with autism spectrum disorder.

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